外科用シーラント市場は、高圧組織層における止血および気流遮断を支えています。生体適合性ポリマーやタンパク質を用いて、脆弱部位や加圧部位における縫合糸/ステープルの補強を行い、入院期間延長(2〜5日間の延長)、疼痛増悪(VAS +2〜3)、費用増加(1症例あたり5,000〜10,000ドル)、死亡率上昇(絶対リスク1〜3%)につながるリークを防止します。フィブリン糊、シアノアクリレート、PEGハイドロゲル、アルブミン-グルタルアルデヒドなどのこれらの薬剤は、共有結合または機械的バリアを形成し、従来の機械的手段では対応できない血管、神経、または肺の欠損部を密封します。特に、結紮が困難な低侵襲ポート(5〜12mm)において顕著です。心臓手術においては、吻合部出血を止血(200〜500mLの節約)、肺切除術によるエアリーク抑制(人工呼吸器装着時間24〜48時間延長)、神経学的硬膜修復による髄液流出の抑制(再手術率5〜10%の減少)、血管補助による末端開存率の向上(血栓症率2%未満)などが挙げられます。手術のミニマリズム化が進む中(腹腔鏡手術やロボット手術が一般外科手術の60%を占める)、シーラントは縫合時間を短縮(5〜10分から1〜2分へ)、肥満患者や抗凝固療法中の患者における有効性を高めています。2025年までに、世界の外科用シーラント市場は、数量ベースのケアと生物学的製剤との相乗効果により、2億〜4億米ドル規模に達すると推定されています。予測によれば、2030 年までの CAGR は 4.5% 〜 8.5% となり、外科手術の処理能力の増加とスプレー可能な技術革新を反映したものとなりますが、湿地での接着の変動によって相殺されます。
外科用シーラントは、心臓(CABG吻合部、24時間で90%のリークフリー)、血管(エンドリーク<5%)、神経(髄液バリア、水頭症10%低下)、肺(気密性肺葉切除、70%の長期リーク防止)、その他(肝臓/婦人科)に適用され、加圧組織の20〜30%の閉鎖を促進します。心臓用シーラントは200mmHgに耐える流動性シーラントを必要とし、血管用シアノアクリレートは脆い端部を接着し、神経用PEGは硬膜の輪郭に適合し、肺用フォームは肺胞内で拡張します。トレンド:MIS用スプレー式ロボット(精度+40%)、抗菌剤負荷によるSSI抑制(15%削減)、小児用生体吸収性シーラント(6〜12週間で分解)。腫瘍切除の件数は毎年 10% 増加しています。
シーラントチェーンが研究開発を開始し、ポリマー化学者がISO 10993に準拠した架橋剤を配合します。3〜5年間のGLP試験を実施し、接着強度が500kPa超、溶解強度が90日未満であることが確認されています。スプレー性向上のためのレオロジーを統合し、リーク圧に関するFDA 510(k)sに準拠しています。
GMP対応設備での製造ではタンパク質/ポリマーを混合し、バクスターの垂直統合によりアルブミン調達を確保します。ガンマ線照射による凍結乾燥と無菌化により2年間の安定性を確保し、マイクロフルイディクスにる拡張性も確保しています。
ACSのデモとシミュレーションによる製品化、1.5日間のLOS短縮に関するHTA(医療技術評価)を実施します。FAERSによるファーマコビジランスにより生体適合性、植物由来接着剤による持続可能性を検証します。
目次
Table of Content
Chapter 1 Executive Summary
Chapter 2 Abbreviation and Acronyms
Chapter 3 Preface
3.1 Research Scope
3.2 Research Sources
3.2.1 Data Sources
3.2.2 Assumptions
3.3 Research Method
Chapter 4 Market Landscape
4.1 Market Overview
4.2 Classification/Types
4.3 Application/End Users
Chapter 5 Market Trend Analysis
5.1 introduction
5.2 Drivers
5.3 Restraints
5.4 Opportunities
5.5 Threats
Chapter 6 industry Chain Analysis
6.1 Upstream/Suppliers Analysis
6.2 Surgical Sealant Analysis
6.2.1 Technology Analysis
6.2.2 Cost Analysis
6.2.3 Market Channel Analysis
6.3 Downstream Buyers/End Users
Chapter 7 Latest Market Dynamics
7.1 Latest News
7.2 Merger and Acquisition
7.3 Planned/Future Project
7.4 Policy Dynamics
Chapter 8 Trading Analysis
8.1 Export of Surgical Sealant by Region
8.2 Import of Surgical Sealant by Region
8.3 Balance of Trade
Chapter 9 Historical and Forecast Surgical Sealant Market in North America (2020-2030)
9.1 Surgical Sealant Market Size
9.2 Surgical Sealant Demand by End Use
9.3 Competition by Players/Suppliers
9.4 Type Segmentation and Price
9.5 Key Countries Analysis
9.5.1 United States
9.5.2 Canada
9.5.3 Mexico
Chapter 10 Historical and Forecast Surgical Sealant Market in South America (2020-2030)
10.1 Surgical Sealant Market Size
10.2 Surgical Sealant Demand by End Use
10.3 Competition by Players/Suppliers
10.4 Type Segmentation and Price
10.5 Key Countries Analysis
10.5.1 Brazil
10.5.2 Argentina
Chapter 11 Historical and Forecast Surgical Sealant Market in Asia & Pacific (2020-2030)
11.1 Surgical Sealant Market Size
11.2 Surgical Sealant Demand by End Use
11.3 Competition by Players/Suppliers
11.4 Type Segmentation and Price
11.5 Key Countries Analysis
11.5.1 China
11.5.2 India
11.5.3 Japan
11.5.4 South Korea
11.5.5 Southest Asia
11.5.6 Australia & New Zealand
Chapter 12 Historical and Forecast Surgical Sealant Market in Europe (2020-2030)
12.1 Surgical Sealant Market Size
12.2 Surgical Sealant Demand by End Use
12.3 Competition by Players/Suppliers
12.4 Type Segmentation and Price
12.5 Key Countries Analysis
12.5.1 Germany
12.5.2 France
12.5.3 United Kingdom
12.5.4 Italy
12.5.5 Spain
12.5.6 Belgium
12.5.7 Netherlands
12.5.8 Austria
12.5.9 Poland
12.5.10 Northern Europe
Chapter 13 Historical and Forecast Surgical Sealant Market in MEA (2020-2030)
13.1 Surgical Sealant Market Size
13.2 Surgical Sealant Demand by End Use
13.3 Competition by Players/Suppliers
13.4 Type Segmentation and Price
13.5 Key Countries Analysis
Chapter 14 Summary For Global Surgical Sealant Market (2020-2025)
14.1 Surgical Sealant Market Size
14.2 Surgical Sealant Demand by End Use
14.3 Competition by Players/Suppliers
14.4 Type Segmentation and Price
Chapter 15 Global Surgical Sealant Market Forecast (2025-2030)
15.1 Surgical Sealant Market Size Forecast
15.2 Surgical Sealant Demand Forecast
15.3 Competition by Players/Suppliers
15.4 Type Segmentation and Price Forecast
Chapter 16 Analysis of Global Key Vendors
16.1 Baxter
16.1.1 Company Profile
16.1.2 Main Business and Surgical Sealant Information
16.1.3 SWOT Analysis of Baxter
16.1.4 Baxter Surgical Sealant Sales, Revenue, Price and Gross Margin (2020-2025)
16.2 Ethicon
16.2.1 Company Profile
16.2.2 Main Business and Surgical Sealant Information
16.2.3 SWOT Analysis of Ethicon
16.2.4 Ethicon Surgical Sealant Sales, Revenue, Price and Gross Margin (2020-2025)
16.3 Grena Ltd
16.3.1 Company Profile
16.3.2 Main Business and Surgical Sealant Information
16.3.3 SWOT Analysis of Grena Ltd
16.3.4 Grena Ltd Surgical Sealant Sales, Revenue, Price and Gross Margin (2020-2025)
16.4 Integra LifeSciences
16.4.1 Company Profile
16.4.2 Main Business and Surgical Sealant Information
16.4.3 SWOT Analysis of Integra LifeSciences
16.4.4 Integra LifeSciences Surgical Sealant Sales, Revenue, Price and Gross Margin (2020-2025)
16.5 BD
16.5.1 Company Profile
16.5.2 Main Business and Surgical Sealant Information
16.5.3 SWOT Analysis of BD
16.5.4 BD Surgical Sealant Sales, Revenue, Price and Gross Margin (2020-2025)
16.6 Artivion
16.6.1 Company Profile
16.6.2 Main Business and Surgical Sealant Information
16.6.3 SWOT Analysis of Artivion
16.6.4 Artivion Surgical Sealant Sales, Revenue, Price and Gross Margin (2020-2025)
Please ask for sample pages for full companies list
Tables and Figures
Table Abbreviation and Acronyms List
Table Research Scope of Surgical Sealant Report
Table Data Sources of Surgical Sealant Report
Table Major Assumptions of Surgical Sealant Report
Figure Market Size Estimated Method
Figure Major Forecasting Factors
Figure Surgical Sealant Picture
Table Surgical Sealant Classification
Table Surgical Sealant Applications List
Table Drivers of Surgical Sealant Market
Table Restraints of Surgical Sealant Market
Table Opportunities of Surgical Sealant Market
Table Threats of Surgical Sealant Market
Table COVID-19 Impact for Surgical Sealant Market
Table Raw Materials Suppliers List
Table Different Production Methods of Surgical Sealant
Table Cost Structure Analysis of Surgical Sealant
Table Key End Users List
Table Latest News of Surgical Sealant Market
Table Merger and Acquisition List
Table Planned/Future Project of Surgical Sealant Market
Table Policy of Surgical Sealant Market
Table 2020-2030 Regional Export of Surgical Sealant
Table 2020-2030 Regional Import of Surgical Sealant
Table 2020-2030 Regional Trade Balance
Figure 2020-2030 Regional Trade Balance
Table 2020-2030 North America Surgical Sealant Market Size and Market Volume List
Figure 2020-2030 North America Surgical Sealant Market Size and CAGR
Figure 2020-2030 North America Surgical Sealant Market Volume and CAGR
Table 2020-2030 North America Surgical Sealant Demand List by Application
Table 2020-2025 North America Surgical Sealant Key Players Sales List
Table 2020-2025 North America Surgical Sealant Key Players Market Share List
Table 2020-2030 North America Surgical Sealant Demand List by Type
Table 2020-2025 North America Surgical Sealant Price List by Type
Table 2020-2030 United States Surgical Sealant Market Size and Market Volume List
Table 2020-2030 United States Surgical Sealant Import & Export List
Table 2020-2030 Canada Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Canada Surgical Sealant Import & Export List
Table 2020-2030 Mexico Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Mexico Surgical Sealant Import & Export List
Table 2020-2030 South America Surgical Sealant Market Size and Market Volume List
Figure 2020-2030 South America Surgical Sealant Market Size and CAGR
Figure 2020-2030 South America Surgical Sealant Market Volume and CAGR
Table 2020-2030 South America Surgical Sealant Demand List by Application
Table 2020-2025 South America Surgical Sealant Key Players Sales List
Table 2020-2025 South America Surgical Sealant Key Players Market Share List
Table 2020-2030 South America Surgical Sealant Demand List by Type
Table 2020-2025 South America Surgical Sealant Price List by Type
Table 2020-2030 Brazil Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Brazil Surgical Sealant Import & Export List
Table 2020-2030 Argentina Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Argentina Surgical Sealant Import & Export List
Table 2020-2030 Chile Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Chile Surgical Sealant Import & Export List
Table 2020-2030 Peru Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Peru Surgical Sealant Import & Export List
Table 2020-2030 Asia & Pacific Surgical Sealant Market Size and Market Volume List
Figure 2020-2030 Asia & Pacific Surgical Sealant Market Size and CAGR
Figure 2020-2030 Asia & Pacific Surgical Sealant Market Volume and CAGR
Table 2020-2030 Asia & Pacific Surgical Sealant Demand List by Application
Table 2020-2025 Asia & Pacific Surgical Sealant Key Players Sales List
Table 2020-2025 Asia & Pacific Surgical Sealant Key Players Market Share List
Table 2020-2030 Asia & Pacific Surgical Sealant Demand List by Type
Table 2020-2025 Asia & Pacific Surgical Sealant Price List by Type
Table 2020-2030 China Surgical Sealant Market Size and Market Volume List
Table 2020-2030 China Surgical Sealant Import & Export List
Table 2020-2030 India Surgical Sealant Market Size and Market Volume List
Table 2020-2030 India Surgical Sealant Import & Export List
Table 2020-2030 Japan Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Japan Surgical Sealant Import & Export List
Table 2020-2030 South Korea Surgical Sealant Market Size and Market Volume List
Table 2020-2030 South Korea Surgical Sealant Import & Export List
Table 2020-2030 Southeast Asia Surgical Sealant Market Size List
Table 2020-2030 Southeast Asia Surgical Sealant Market Volume List
Table 2020-2030 Southeast Asia Surgical Sealant Import List
Table 2020-2030 Southeast Asia Surgical Sealant Export List
Table 2020-2030 Australia & New Zealand Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Australia & New Zealand Surgical Sealant Import & Export List
Table 2020-2030 Europe Surgical Sealant Market Size and Market Volume List
Figure 2020-2030 Europe Surgical Sealant Market Size and CAGR
Figure 2020-2030 Europe Surgical Sealant Market Volume and CAGR
Table 2020-2030 Europe Surgical Sealant Demand List by Application
Table 2020-2025 Europe Surgical Sealant Key Players Sales List
Table 2020-2025 Europe Surgical Sealant Key Players Market Share List
Table 2020-2030 Europe Surgical Sealant Demand List by Type
Table 2020-2025 Europe Surgical Sealant Price List by Type
Table 2020-2030 Germany Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Germany Surgical Sealant Import & Export List
Table 2020-2030 France Surgical Sealant Market Size and Market Volume List
Table 2020-2030 France Surgical Sealant Import & Export List
Table 2020-2030 United Kingdom Surgical Sealant Market Size and Market Volume List
Table 2020-2030 United Kingdom Surgical Sealant Import & Export List
Table 2020-2030 Italy Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Italy Surgical Sealant Import & Export List
Table 2020-2030 Spain Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Spain Surgical Sealant Import & Export List
Table 2020-2030 Belgium Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Belgium Surgical Sealant Import & Export List
Table 2020-2030 Netherlands Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Netherlands Surgical Sealant Import & Export List
Table 2020-2030 Austria Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Austria Surgical Sealant Import & Export List
Table 2020-2030 Poland Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Poland Surgical Sealant Import & Export List
Table 2020-2030 Northern Europe Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Northern Europe Surgical Sealant Import & Export List
Table 2020-2030 MEA Surgical Sealant Market Size and Market Volume List
Figure 2020-2030 MEA Surgical Sealant Market Size and CAGR
Figure 2020-2030 MEA Surgical Sealant Market Volume and CAGR
Table 2020-2030 MEA Surgical Sealant Demand List by Application
Table 2020-2025 MEA Surgical Sealant Key Players Sales List
Table 2020-2025 MEA Surgical Sealant Key Players Market Share List
Table 2020-2030 MEA Surgical Sealant Demand List by Type
Table 2020-2025 MEA Surgical Sealant Price List by Type
Table 2020-2030 Egypt Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Egypt Surgical Sealant Import & Export List
Table 2020-2030 Israel Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Israel Surgical Sealant Import & Export List
Table 2020-2030 South Africa Surgical Sealant Market Size and Market Volume List
Table 2020-2030 South Africa Surgical Sealant Import & Export List
Table 2020-2030 Gulf Cooperation Council Countries Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Gulf Cooperation Council Countries Surgical Sealant Import & Export List
Table 2020-2030 Turkey Surgical Sealant Market Size and Market Volume List
Table 2020-2030 Turkey Surgical Sealant Import & Export List
Table 2020-2025 Global Surgical Sealant Market Size List by Region
Table 2020-2025 Global Surgical Sealant Market Size Share List by Region
Table 2020-2025 Global Surgical Sealant Market Volume List by Region
Table 2020-2025 Global Surgical Sealant Market Volume Share List by Region
Table 2020-2025 Global Surgical Sealant Demand List by Application
Table 2020-2025 Global Surgical Sealant Demand Market Share List by Application
Table 2020-2025 Global Surgical Sealant Key Vendors Sales List
Table 2020-2025 Global Surgical Sealant Key Vendors Sales Share List
Figure 2020-2025 Global Surgical Sealant Market Volume and Growth Rate
Table 2020-2025 Global Surgical Sealant Key Vendors Revenue List
Figure 2020-2025 Global Surgical Sealant Market Size and Growth Rate
Table 2020-2025 Global Surgical Sealant Key Vendors Revenue Share List
Table 2020-2025 Global Surgical Sealant Demand List by Type
Table 2020-2025 Global Surgical Sealant Demand Market Share List by Type
Table 2020-2025 Regional Surgical Sealant Price List
Table 2025-2030 Global Surgical Sealant Market Size List by Region
Table 2025-2030 Global Surgical Sealant Market Size Share List by Region
Table 2025-2030 Global Surgical Sealant Market Volume List by Region
Table 2025-2030 Global Surgical Sealant Market Volume Share List by Region
Table 2025-2030 Global Surgical Sealant Demand List by Application
Table 2025-2030 Global Surgical Sealant Demand Market Share List by Application
Table 2025-2030 Global Surgical Sealant Key Vendors Sales List
Table 2025-2030 Global Surgical Sealant Key Vendors Sales Share List
Figure 2025-2030 Global Surgical Sealant Market Volume and Growth Rate
Table 2025-2030 Global Surgical Sealant Key Vendors Revenue List
Figure 2025-2030 Global Surgical Sealant Market Size and Growth Rate
Table 2025-2030 Global Surgical Sealant Key Vendors Revenue Share List
Table 2025-2030 Global Surgical Sealant Demand List by Type
Table 2025-2030 Global Surgical Sealant Demand Market Share List by Type
Table 2025-2030 Surgical Sealant Regional Price List
Table Baxter Information
Table SWOT Analysis of Baxter
Table 2020-2025 Baxter Surgical Sealant Sale Volume Price Cost Revenue
Figure 2020-2025 Baxter Surgical Sealant Sale Volume and Growth Rate
Figure 2020-2025 Baxter Surgical Sealant Market Share
Table Ethicon Information
Table SWOT Analysis of Ethicon
Table 2020-2025 Ethicon Surgical Sealant Sale Volume Price Cost Revenue
Figure 2020-2025 Ethicon Surgical Sealant Sale Volume and Growth Rate
Figure 2020-2025 Ethicon Surgical Sealant Market Share
Table Grena Ltd Information
Table SWOT Analysis of Grena Ltd
Table 2020-2025 Grena Ltd Surgical Sealant Sale Volume Price Cost Revenue
Figure 2020-2025 Grena Ltd Surgical Sealant Sale Volume and Growth Rate
Figure 2020-2025 Grena Ltd Surgical Sealant Market Share
Table Integra LifeSciences Information
Table SWOT Analysis of Integra LifeSciences
Table 2020-2025 Integra LifeSciences Surgical Sealant Sale Volume Price Cost Revenue
Figure 2020-2025 Integra LifeSciences Surgical Sealant Sale Volume and Growth Rate
Figure 2020-2025 Integra LifeSciences Surgical Sealant Market Share
Table BD Information
Table SWOT Analysis of BD
Table 2020-2025 BD Surgical Sealant Sale Volume Price Cost Revenue
Figure 2020-2025 BD Surgical Sealant Sale Volume and Growth Rate
Figure 2020-2025 BD Surgical Sealant Market Share
Table Artivion Information
Table SWOT Analysis of Artivion
Table 2020-2025 Artivion Surgical Sealant Sale Volume Price Cost Revenue
Figure 2020-2025 Artivion Surgical Sealant Sale Volume and Growth Rate
Figure 2020-2025 Artivion Surgical Sealant Market Share