大うつ病性障害（MDD）市場は、モノアミン神経伝達物質と補助的な経路を調節する薬物療法を中心に展開しており、持続的な悲しみ、快楽消失、精神運動機能の変化といった中核症状を緩和します。MDD患者は世界で2億8000万人に上り、高所得国では生涯有病率が20%近くに達しています。これらの治療法は、シナプスセロトニンを増強する選択的セロトニン再取り込み阻害薬（SSRI）から、D2/5HT1A作動薬を介してドーパミンとグルタミン酸のバランスを整える非定型抗精神病薬（AAP）まで多岐にわたり、第一選択薬として50〜60%の奏効率を達成していますが、治療抵抗性うつ病では30%の患者に増強療法が必要となります。市場の厚みは、不眠症などの身体的症状に対処するマルチモーダルな選択肢に起因しており、認知障害に対するマルチモーダルボルチオキセチンの革新は患者の70%に影響を与えています。実際の寛解率は30%前後で推移しており、BDNFレベルなどのバイオマーカーを指標としたパーソナライゼーションの促進に加え、デジタルセラピューティクスが服薬遵守の追跡に統合されています。2025年までに、世界のMDD市場は40億米ドルから70億米ドルに達すると推定され、2030年までの年平均成長率（CAGR）は3.5%から5.5%と予測されています。この堅調な成長は、パンデミック後のメンタルヘルス危機における診断件数の急増（若年層では25%増加）と、APAガイドラインによる速効性エスケタミン補助薬の推奨を反映していますが、ジェネリック医薬品の飽和によりSSRIの売上高の40%が減少する一方で、その効果は相殺されています。この分野では、スティグマを乗り越え、50%の症例で助けを求めることを減らしつつ、遠隔精神医学を活用してアクセスを3倍に拡大しています。MDD治療は精神医学の生物心理社会学的進化を象徴するものであり、持続的な寛解によって機能年数を5〜10年延長しますが、併存疾患の40%において多剤併用リスクは依然として残っています。
MDDバリューチェーンは、セロトニンアッセイから寛解追跡まで、神経薬理学と心理社会的統合を融合させています。上流研究開発では、5HT1A占有率のPETイメージング、サブタイプのAI表現型解析を導入しています。HAM-Dスケールに基づく第III相試験は5億ドルの費用がかかり、FDAはBTD（医薬品開発計画）の承認を迅速化しています。臨床開発では、STAR*D設計、炎症のCRPなどのバイオマーカー、希少疾患のEMAのPRIMEが活用されています。中流部門では、ボルチオキセチンのアザピンドールを鈴木カップリング反応で合成し、HPLCで99.8%の収率を達成しています。インドのCMOは100トン規模で生産しています。製剤はTCAを腸溶コーティングし、ブリスターパックに詰めます。下流部門は薬局への物流、リリーのアドヒアランスアプリです。APA学会を通じたマーケティング、HEORはQALYあたり5万ドルの収益を上げています。テレサイキアや自殺ホットライン、SSRIリスクに関するFAERSを支援します。AbbVieのような垂直統合企業は、試験からRWEまでを効率化します。
目次
Table of Contents
Chapter 1 Executive Summary
Chapter 2 Abbreviation and Acronyms
Chapter 3 Preface
3.1 Research Scope
3.2 Research Sources
3.2.1 Data Sources
3.2.2 Assumptions
3.3 Research Method
Chapter Four Market Landscape
4.1 Market Overview
4.2 Classification/Types
4.3 Application/End Users
Chapter 5 Market Trend Analysis
5.1 Introduction
5.2 Drivers
5.3 Restraints
5.4 Opportunities
5.5 Threats
Chapter 6 Industry Chain Analysis
6.1 Upstream/Suppliers Analysis
6.2 Major Depressive Disorder (MDD) Analysis
6.2.1 Technology Analysis
6.2.2 Cost Analysis
6.2.3 Market Channel Analysis
6.3 Downstream Buyers/End Users
Chapter 7 Latest Market Dynamics
7.1 Latest News
7.2 Merger and Acquisition
7.3 Planned/Future Project
7.4 Policy Dynamics
Chapter 8 Historical and Forecast Major Depressive Disorder (MDD) Market in North America (2020-2030)
8.1 Major Depressive Disorder (MDD) Market Size
8.2 Major Depressive Disorder (MDD) Market by End Use
8.3 Competition by Players/Suppliers
8.4 Major Depressive Disorder (MDD) Market Size by Type
8.5 Key Countries Analysis
8.5.1 United States
8.5.2 Canada
8.5.3 Mexico
Chapter 9 Historical and Forecast Major Depressive Disorder (MDD) Market in South America (2020-2030)
9.1 Major Depressive Disorder (MDD) Market Size
9.2 Major Depressive Disorder (MDD) Market by End Use
9.3 Competition by Players/Suppliers
9.4 Major Depressive Disorder (MDD) Market Size by Type
9.5 Key Countries Analysis
9.5.1 Brazil
9.5.2 Argentina
Chapter 10 Historical and Forecast Major Depressive Disorder (MDD) Market in Asia & Pacific (2020-2030)
10.1 Major Depressive Disorder (MDD) Market Size
10.2 Major Depressive Disorder (MDD) Market by End Use
10.3 Competition by Players/Suppliers
10.4 Major Depressive Disorder (MDD) Market Size by Type
10.5 Key Countries Analysis
10.5.1 China
10.5.2 India
10.5.3 Japan
10.5.4 South Korea
10.5.5 Southest Asia
10.5.6 Australia
Chapter 11 Historical and Forecast Major Depressive Disorder (MDD) Market in Europe (2020-2030)
11.1 Major Depressive Disorder (MDD) Market Size
11.2 Major Depressive Disorder (MDD) Market by End Use
11.3 Competition by Players/Suppliers
11.4 Major Depressive Disorder (MDD) Market Size by Type
11.5 Key Countries Analysis
11.5.1 Germany
11.5.2 France
11.5.3 United Kingdom
11.5.4 Italy
11.5.5 Spain
11.5.6 Belgium
11.5.7 Netherlands
11.5.8 Austria
11.5.9 Poland
11.5.10 Russia
Chapter 12 Historical and Forecast Major Depressive Disorder (MDD) Market in MEA (2020-2030)
12.1 Major Depressive Disorder (MDD) Market Size
12.2 Major Depressive Disorder (MDD) Market by End Use
12.3 Competition by Players/Suppliers
12.4 Major Depressive Disorder (MDD) Market Size by Type
Chapter 13 Summary For Global Major Depressive Disorder (MDD) Market (2020-2025)
13.1 Major Depressive Disorder (MDD) Market Size
13.2 Major Depressive Disorder (MDD) Market by End Use
13.3 Competition by Players/Suppliers
13.4 Major Depressive Disorder (MDD) Market Size by Type
Chapter 14 Global Major Depressive Disorder (MDD) Market Forecast (2025-2030)
14.1 Major Depressive Disorder (MDD) Market Size Forecast
14.2 Major Depressive Disorder (MDD) Application Forecast
14.3 Competition by Players/Suppliers
14.4 Major Depressive Disorder (MDD) Type Forecast
Chapter 15 Analysis of Global Key Vendors
15.1 Eli Lilly
15.1.1 Company Profile
15.1.2 Main Business and Major Depressive Disorder (MDD) Information
15.1.3 SWOT Analysis of Eli Lilly
15.1.4 Eli Lilly Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.2 AbbVie
15.2.1 Company Profile
15.2.2 Main Business and Major Depressive Disorder (MDD) Information
15.2.3 SWOT Analysis of AbbVie
15.2.4 AbbVie Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.3 Pfizer
15.3.1 Company Profile
15.3.2 Main Business and Major Depressive Disorder (MDD) Information
15.3.3 SWOT Analysis of Pfizer
15.3.4 Pfizer Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.4 Lundbeck
15.4.1 Company Profile
15.4.2 Main Business and Major Depressive Disorder (MDD) Information
15.4.3 SWOT Analysis of Lundbeck
15.4.4 Lundbeck Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.5 Cheplapharm
15.5.1 Company Profile
15.5.2 Main Business and Major Depressive Disorder (MDD) Information
15.5.3 SWOT Analysis of Cheplapharm
15.5.4 Cheplapharm Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.6 Viatris
15.6.1 Company Profile
15.6.2 Main Business and Major Depressive Disorder (MDD) Information
15.6.3 SWOT Analysis of Viatris
15.6.4 Viatris Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.7 Apotex
15.7.1 Company Profile
15.7.2 Main Business and Major Depressive Disorder (MDD) Information
15.7.3 SWOT Analysis of Apotex
15.7.4 Apotex Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.8 OTSUKA
15.8.1 Company Profile
15.8.2 Main Business and Major Depressive Disorder (MDD) Information
15.8.3 SWOT Analysis of OTSUKA
15.8.4 OTSUKA Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.9 Sandoz
15.9.1 Company Profile
15.9.2 Main Business and Major Depressive Disorder (MDD) Information
15.9.3 SWOT Analysis of Sandoz
15.9.4 Sandoz Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.10 Teva Pharmaceuticals
15.10.1 Company Profile
15.10.2 Main Business and Major Depressive Disorder (MDD) Information
15.10.3 SWOT Analysis of Teva Pharmaceuticals
15.10.4 Teva Pharmaceuticals Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.11 Dr. Reddy's Laboratories
15.11.1 Company Profile
15.11.2 Main Business and Major Depressive Disorder (MDD) Information
15.11.3 SWOT Analysis of Dr. Reddy's Laboratories
15.11.4 Dr. Reddy's Laboratories Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.12 Sun Pharma
15.12.1 Company Profile
15.12.2 Main Business and Major Depressive Disorder (MDD) Information
15.12.3 SWOT Analysis of Sun Pharma
15.12.4 Sun Pharma Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
15.13 Glenmark Pharma
15.13.1 Company Profile
15.13.2 Main Business and Major Depressive Disorder (MDD) Information
15.13.3 SWOT Analysis of Glenmark Pharma
15.13.4 Glenmark Pharma Major Depressive Disorder (MDD) Revenue, Gross Margin and Market Share (2020-2025)
Please ask for sample pages for full companies list
Tables and Figures
Table Abbreviation and Acronyms
Table Research Scope of Major Depressive Disorder (MDD) Report
Table Data Sources of Major Depressive Disorder (MDD) Report
Table Major Assumptions of Major Depressive Disorder (MDD) Report
Figure Market Size Estimated Method
Figure Major Forecasting Factors
Figure Major Depressive Disorder (MDD) Picture
Table Major Depressive Disorder (MDD) Classification
Table Major Depressive Disorder (MDD) Applications
Table Drivers of Major Depressive Disorder (MDD) Market
Table Restraints of Major Depressive Disorder (MDD) Market
Table Opportunities of Major Depressive Disorder (MDD) Market
Table Threats of Major Depressive Disorder (MDD) Market
Table Raw Materials Suppliers
Table Different Production Methods of Major Depressive Disorder (MDD)
Table Cost Structure Analysis of Major Depressive Disorder (MDD)
Table Key End Users
Table Latest News of Major Depressive Disorder (MDD) Market
Table Merger and Acquisition
Table Planned/Future Project of Major Depressive Disorder (MDD) Market
Table Policy of Major Depressive Disorder (MDD) Market
Table 2020-2030 North America Major Depressive Disorder (MDD) Market Size
Figure 2020-2030 North America Major Depressive Disorder (MDD) Market Size and CAGR
Table 2020-2030 North America Major Depressive Disorder (MDD) Market Size by Application
Table 2020-2025 North America Major Depressive Disorder (MDD) Key Players Revenue
Table 2020-2025 North America Major Depressive Disorder (MDD) Key Players Market Share
Table 2020-2030 North America Major Depressive Disorder (MDD) Market Size by Type
Table 2020-2030 United States Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Canada Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Mexico Major Depressive Disorder (MDD) Market Size
Table 2020-2030 South America Major Depressive Disorder (MDD) Market Size
Figure 2020-2030 South America Major Depressive Disorder (MDD) Market Size and CAGR
Table 2020-2030 South America Major Depressive Disorder (MDD) Market Size by Application
Table 2020-2025 South America Major Depressive Disorder (MDD) Key Players Revenue
Table 2020-2025 South America Major Depressive Disorder (MDD) Key Players Market Share
Table 2020-2030 South America Major Depressive Disorder (MDD) Market Size by Type
Table 2020-2030 Brazil Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Argentina Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Asia & Pacific Major Depressive Disorder (MDD) Market Size
Figure 2020-2030 Asia & Pacific Major Depressive Disorder (MDD) Market Size and CAGR
Table 2020-2030 Asia & Pacific Major Depressive Disorder (MDD) Market Size by Application
Table 2020-2025 Asia & Pacific Major Depressive Disorder (MDD) Key Players Revenue
Table 2020-2025 Asia & Pacific Major Depressive Disorder (MDD) Key Players Market Share
Table 2020-2030 Asia & Pacific Major Depressive Disorder (MDD) Market Size by Type
Table 2020-2030 China Major Depressive Disorder (MDD) Market Size
Table 2020-2030 India Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Japan Major Depressive Disorder (MDD) Market Size
Table 2020-2030 South Korea Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Southeast Asia Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Australia Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Europe Major Depressive Disorder (MDD) Market Size
Figure 2020-2030 Europe Major Depressive Disorder (MDD) Market Size and CAGR
Table 2020-2030 Europe Major Depressive Disorder (MDD) Market Size by Application
Table 2020-2025 Europe Major Depressive Disorder (MDD) Key Players Revenue
Table 2020-2025 Europe Major Depressive Disorder (MDD) Key Players Market Share
Table 2020-2030 Europe Major Depressive Disorder (MDD) Market Size by Type
Table 2020-2030 Germany Major Depressive Disorder (MDD) Market Size
Table 2020-2030 France Major Depressive Disorder (MDD) Market Size
Table 2020-2030 United Kingdom Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Italy Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Spain Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Belgium Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Netherlands Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Austria Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Poland Major Depressive Disorder (MDD) Market Size
Table 2020-2030 Russia Major Depressive Disorder (MDD) Market Size
Table 2020-2030 MEA Major Depressive Disorder (MDD) Market Size
Figure 2020-2030 MEA Major Depressive Disorder (MDD) Market Size and CAGR
Table 2020-2030 MEA Major Depressive Disorder (MDD) Market Size by Application
Table 2020-2025 MEA Major Depressive Disorder (MDD) Key Players Revenue
Table 2020-2025 MEA Major Depressive Disorder (MDD) Key Players Market Share
Table 2020-2030 MEA Major Depressive Disorder (MDD) Market Size by Type
Table 2020-2025 Global Major Depressive Disorder (MDD) Market Size by Region
Table 2020-2025 Global Major Depressive Disorder (MDD) Market Size Share by Region
Table 2020-2025 Global Major Depressive Disorder (MDD) Market Size by Application
Table 2020-2025 Global Major Depressive Disorder (MDD) Market Share by Application
Table 2020-2025 Global Major Depressive Disorder (MDD) Key Vendors Revenue
Figure 2020-2025 Global Major Depressive Disorder (MDD) Market Size and Growth Rate
Table 2020-2025 Global Major Depressive Disorder (MDD) Key Vendors Market Share
Table 2020-2025 Global Major Depressive Disorder (MDD) Market Size by Type
Table 2020-2025 Global Major Depressive Disorder (MDD) Market Share by Type
Table 2025-2030 Global Major Depressive Disorder (MDD) Market Size by Region
Table 2025-2030 Global Major Depressive Disorder (MDD) Market Size Share by Region
Table 2025-2030 Global Major Depressive Disorder (MDD) Market Size by Application
Table 2025-2030 Global Major Depressive Disorder (MDD) Market Share by Application
Table 2025-2030 Global Major Depressive Disorder (MDD) Key Vendors Revenue
Figure 2025-2030 Global Major Depressive Disorder (MDD) Market Size and Growth Rate
Table 2025-2030 Global Major Depressive Disorder (MDD) Key Vendors Market Share
Table 2025-2030 Global Major Depressive Disorder (MDD) Market Size by Type
Table 2025-2030 Major Depressive Disorder (MDD) Global Market Share by Type
Table Eli Lilly Information
Table SWOT Analysis of Eli Lilly
Table 2020-2025 Eli Lilly Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Eli Lilly Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Eli Lilly Major Depressive Disorder (MDD) Market Share
Table AbbVie Information
Table SWOT Analysis of AbbVie
Table 2020-2025 AbbVie Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 AbbVie Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 AbbVie Major Depressive Disorder (MDD) Market Share
Table Pfizer Information
Table SWOT Analysis of Pfizer
Table 2020-2025 Pfizer Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Pfizer Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Pfizer Major Depressive Disorder (MDD) Market Share
Table Lundbeck Information
Table SWOT Analysis of Lundbeck
Table 2020-2025 Lundbeck Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Lundbeck Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Lundbeck Major Depressive Disorder (MDD) Market Share
Table Cheplapharm Information
Table SWOT Analysis of Cheplapharm
Table 2020-2025 Cheplapharm Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Cheplapharm Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Cheplapharm Major Depressive Disorder (MDD) Market Share
Table Viatris Information
Table SWOT Analysis of Viatris
Table 2020-2025 Viatris Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Viatris Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Viatris Major Depressive Disorder (MDD) Market Share
Table Apotex Information
Table SWOT Analysis of Apotex
Table 2020-2025 Apotex Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Apotex Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Apotex Major Depressive Disorder (MDD) Market Share
Table OTSUKA Information
Table SWOT Analysis of OTSUKA
Table 2020-2025 OTSUKA Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 OTSUKA Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 OTSUKA Major Depressive Disorder (MDD) Market Share
Table Sandoz Information
Table SWOT Analysis of Sandoz
Table 2020-2025 Sandoz Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Sandoz Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Sandoz Major Depressive Disorder (MDD) Market Share
Table Teva Pharmaceuticals Information
Table SWOT Analysis of Teva Pharmaceuticals
Table 2020-2025 Teva Pharmaceuticals Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Teva Pharmaceuticals Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Teva Pharmaceuticals Major Depressive Disorder (MDD) Market Share
Table Dr. Reddy's Laboratories Information
Table SWOT Analysis of Dr. Reddy's Laboratories
Table 2020-2025 Dr. Reddy's Laboratories Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Dr. Reddy's Laboratories Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Dr. Reddy's Laboratories Major Depressive Disorder (MDD) Market Share
Table Sun Pharma Information
Table SWOT Analysis of Sun Pharma
Table 2020-2025 Sun Pharma Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Sun Pharma Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Sun Pharma Major Depressive Disorder (MDD) Market Share
Table Glenmark Pharma Information
Table SWOT Analysis of Glenmark Pharma
Table 2020-2025 Glenmark Pharma Major Depressive Disorder (MDD) Revenue Gross Profit Margin
Figure 2020-2025 Glenmark Pharma Major Depressive Disorder (MDD) Revenue and Growth Rate
Figure 2020-2025 Glenmark Pharma Major Depressive Disorder (MDD) Market Share
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