SPI Infoamtion

Table of Contents

Executive summary

Market overview
Competitive landscape & market dynamics
The bioinformatics tools market
The bioinformatics
The bioinformatics service market
The bioinformatics
Regional analysis of the bioinformatics
Company profiles

Chapter 1 Market overview

Summary
Introduction

Defining the bioinformatics market
Market evolution increases use of bioinformatics

Bioinformatics and drug development

Sequencing tools are high priority
Bioinformatics database management tools

Bioinformatics patent analysis

Genomics remains the key segment
High market presence of Japanese market players
Bioinformatics service outsourcing shifting to Asian markets

Market Size

Chapter 2 Competitive landscape & market dynamics

Summary
Introduction
Competitive landscape

Recent mergers and acquisitions
Recent product, technology and service launches

Market drivers

Need for integrated data-handling tools for drug discovery
Growth in genomics and proteomics industry
Wide applications in drug discovery and development
Government support for R&D
Biomarker discovery enables the development of safe drugs
Developments in internet and IT
Emergence of high-throughput screening
Other drivers

Resistors of market growth

Common, well-defined data formats are needed
Need for trained resources compound operational costs
Saturation of pharmaceutical markets reduces adoption rate
Restricted range of product/service offerings
Other restraints to market growth

Growth opportunities

Pressure to escalate drug research productivity
Drug development value chain to widen opportunities
High market demand for integrated systems and solutions
Chemogenomics poses vast opportunity for growth
Applications in diversified areas to expand the user base
Data overload in the field of research

Chapter 3 The bioinformatics tools market

Summary
Introduction

Growth drivers

Need for better output quality in drug discovery
Integration of bioinformatics resources
Application of bioinformatic tools in the life sciences market

Resistors of growth

Complex operations of bioinformatic tools restricts growth
High price of analytical solutions may not be feasible

Sequence analysis tools

DNA sequence analysis tools

Sequence alignment
Gene detection
Restriction, and repeats and unusual patterns detection
Transcriptional elements detection
tRNA detection

Protein function assignment

Protein-protein interaction
Pattern, motif, profiles, domains and families search
Search, computation and analysis of pathways
Protein annotation
Automatic alerts for related new sequences

3D structure analysis and modeling tools

3D viewers
3D homology modeling
3D analysis

RNA analysis tool
Microarray data analysis
Phylogenetic analysis

Multiple sequence alignment
Organism classification

Sequence alignment tools

Sequence analysis (alignment)

Multiple sequence alignment
Phylogenetic tree building
Consensus sequence and translation

Lab end-sequence analysis

Primer design
Cloning
Contig assembly

Sequence manipulation tools

Sequence analysis (including sequence manipulation)
Sequence manipulation
Format conversion
Random sequences

Structural analysis tools

Sequence visualization tools

3D protein structure
Dot plots
Graphical and phylogenetic tree viewers and editors

Primary sequence analysis
Physicochemical property alignment
Alignment tools
Predicting secondary structure sequences

Other bioinformatics tools

Visualization tools

Database viewers
Sequence viewers
Molecular viewers

Physical mapping software

Chapter 4 The bioinforma content/database market

Summary
Introduction

Growth drivers

Exponential growth in the proteomics data and databases
Data integration devices needed for in-house solutions
Growth in the clinical trials industry supports the market

Specialized databases

Specialized sequence databases
Genome databases

Collections
Model organism databases

Specialized protein databases

Proteome databases
Protein classification databases
Specific protein family databases

Specialized structural databases
Microarray databases
Pathways databases
2D-PAGE databases

General databases

Primary sequence databases
Protein sequence databases
3D structure databases
Carbohydrate databases

Chapter 5 The bioinformatics services market

Summary
Introduction

Growth drivers

Growing trend towards consultancy
Requirement for highly efficient data-mining tools
Need for total integration & warehousing solutions

Data analysis services

Genomics data analysis
Proteomics data analysis
Microarray data analysis
Modeling & computational bioinformatics services

Sequencing services

High-throughput screening
Multiple sequence alignment
Resequencing (SNP profiling)
Primer walking
Expression profile clustering
Shotgun sequencing

Database management services

Conception and realization
Development of user interface
Maintenance
Backup systems
Migration

Other services

Security systems
Data-mining services
Infrastructure integration services
Knowledge management

Chapter 6 The bioinformatics applications market

Summary
Introduction

Global market dynamics
Growth drivers

Rapid development of molecular diagnostics market
Development in personalized medicine
Specific medicines developed to treat the source of disease

Resistors of growth

Need for more holistic solutions
Bioinformatics considered to be for specialized applications only

Opportunities

Application in the military
Bioinformatics in epidemiology
Integration of systems biology with bioinformatics

Molecular medicine

Global market

US
Europe
Asia

Preventive medicine
Gene therapy

Growth drivers

Biomarker discovery helps gene therapy to determine disease
candidates
Demand for gene therapy treatment necessitates bioinformatics
application

Opportunities

Data proliferation in the field of gene therapy
Declining growth of gene therapy market

Drug development

Growth drivers

Drastic cost reduction in the process of drug discovery
Data processing needs in the drug development process

Virtual high-throughput screening
Sequence analysis
Similarity searches
Drug lead optimization
Physicochemical modeling
Drug bioavailability and bioactivity

Other applications

Chapter 7 Regional analysis of the bioinformatics market

Summary
Introduction
North America
Europe
Asia

India and China

The Indian bioinformatics industry
Business opportunities in India and China
Growth drivers
Growth resistors

Rest of the World

Chapter 8 Company profiles

Summary
3rd Millennium Inc.

Company overview
Products and services
Company strategy

Accelrys, Inc.

Company overview
Products and services
Company strategy

Affymetrix

Company overview
Products and services
Company strategy

Agilent Technologies, Inc.

Company overview
Products and services
Company strategy

Animech Technologies AB

Company overview
Products and services
Company strategy

Bruker Daltonics inc.

Company overview
Products and services
Company strategy

Ariadne Genomics

Company overview
Products and services
Company strategy

Biobase GmbH

Company overview
Products and services
Company strategy

BioDiscovery, Inc.

Company overview
Products and services
Company strategy

Bioinformatics Solutions Inc.

Company overview
Products and services
Company strategy

Biomatters Ltd

Company overview
Products and services
Company strategy

Biomax Informatics AG

Company overview
Products and services
Company strategy

BioWisdom Ltd

Company overview
Products and services
Company strategy

Celera Genomics Corporation

Company overview
Products and services
Company strategy

CLC bio

Company overview
Products and services
Company strategy

Geospiza, Inc.

Company overview
Products and services
Company strategy

Clontech Laboratories, Inc.

Company overview
Products and services
Company strategy

Definiens AG

Company overview
Products and services
Company strategy

DNASTAR, INC.

Company overview
Products and services
Company strategy

Expression Analysis, Inc.

Company overview
Products and services
Company strategy

Gene Logic

Company overview
Products and services
Company strategy

Genedata AG

Company overview
Products and services
Company strategy

GeneGo

Company overview
Products and services
Company strategy

Geneva Bioinformatics SA

Company overview
Products and services
Company strategy

Genologics Life Sciences Software

Company overview
Products and services
Company strategy

Genomatix Software Inc

Company overview
Products and services
Company strategy

GenomeQuest, Inc

Company overview
Products and services
Company strategy

Helicos Biosciences Corporation

Company overview
Products and services
Company strategy

Illumina Inc.

Company overview
Products and services
Company strategy

InforMax Inc.

Company overview
Products and services
Company strategy

Nucleics Pvt Ltd

Company overview
Products and services
Company strategy

Inforsense Limited

Company overview
Products and services
Company strategy

Kinexus Bioinformatics Corporation

Company overview
Products and services
Company strategy

MDS Inc.

Company overview
Products and services
Company strategy

Miraibio Group

Company overview
Products and services
Company strategy

Golden Helix, Inc

Company overview
Products and services
Company strategy

Invitrogen Corporation

Company overview
Products and services
Company strategy

Molegro

Company overview
Products and services
Company strategy

Nonlinear Dynamics

Company overview
Products and services
Company strategy

Textco Biosoftware, Inc.

Company overview
Products and services
Company strategy

Numerical Algorithms Group Ltd

Company overview
Products and services
Company strategy

Ocimum Biosolutions Ltd.

Company overview
Products and services
Company strategy

Partek Inc.

Company overview
Products and services
Company strategy

Phase Forward Inc.

Company overview
Products and services
Company strategy

Premier Biosoft International

Company overview
Products and services
Company strategy

Protein Forest Inc.

Company overview
Products and services
Company strategy

Rosetta Biosoftware

Company overview
Products and services
Company strategy

Silicon Graphics Inc.

Company overview
Products and services
Company strategy

Softberry Inc.

Company overview
Products and services
Company strategy

Softgenetics, LLC.

Company overview
Products and services
Company strategy

Strand Life Sciences

Company overview
Products and services
Company strategy

Synamatix Sdn Bhd

Company overview
Products and services
Company strategy

Teranode Corporation

Company overview
Products and services
Company strategy

Tibco Spotfire

Company overview
Products and services
Company strategy

Tripos International

Company overview
Products and services
Company strategy

Chapter 9 Appendix

Index

List of Figures
Figure 1.1: Bioinformatics components
Figure 1.2: Bioinformatics market segmentation
Figure 1.3: Market transition impacting bioinformatics market
Figure 1.4: Role of bioinformatics in drug development process
Figure 1.5: Comparative analysis of the bioinformatics application market
Figure 1.6: Relative importance of bioinformatic tool features (2009 vs 2014)
Figure 1.7: Market size versus growth in the bioinformatic tools market
Figure 1.8: Market size versus growth in the bioinformatic services market
Figure 1.9: Patents approved by technology (%), 2004 vs 2008
Figure 1.10: Patents approved by company, 2004-08
Figure 1.11: Regional approval of patents, 2004 vs 2008
Figure 2.12: Strategic focus of bioinformatics companies, 2008-09
Figure 3.13: Bioinformatic tools market dynamics
Figure 3.14: Level of market attractiveness of bioinformatic tools
Figure 3.15: Sequence analysis process and application of bioinformatic tools
Figure 4.16: Bioinformatics content/database market dynamics
Figure 5.17: Bioinformatics services market dynamics
Figure 5.18: Level of attractiveness of the bioinformatics services market
Figure 6.19: Regional distribution of bioinformatics applications market, 2009 and 2014
Figure 6.20: Global scenario for molecular medicine
Figure 6.21: Level of market attractiveness for other bioinformatic applications
Figure 7.22: Market revenues for Asia, 2008 vs 2014
Figure 7.23: Comparative impact of business environment (India and China), 2009
Figure 7.24: Indian bioinformatics market structure
Figure 7.25: Source of revenue for Indian bioinformatics firms
Figure 7.26: Major opportunities for Indian IT market players
Figure 7.27: Business opportunities in India and China
Figure 7.28: Key trends impacting India and China

List of Tables
Table 1.1: Global bioinformatics market by submarket, 2007-14($m)
Table 2.2: Recent mergers and acquisitions, 2008-09
Table 2.3: New product, technology or service launches, 2008-09
Table 2.4: New product, technology or service launches, 2008-09 (contd 1)
Table 2.5: New product, technology or service launches, 2008-09 (contd 2)
Table 2.6: New product, technology or service launches, 2008-09 (contd 3)
Table 3.7: Global bioinformatic tools market by product, 2007-14 ($m)
Table 3.8: Bioinformatic tools market by region, 2007-14 ($m)
Table 3.9: Global sequence analysis tools market by product function,
Table 3.10: Sequence analysis tools market by region, 2007-14 ($m)
Table 3.11: Global DNA sequence analysis tools market by product function, 2007-14 ($m)
Table 3.12: DNA sequence analysis tools market by region, 2007-14 ($m)
Table 3.13: Sequence alignment market by region, 2007-14 ($m)
Table 3.14: Gene detection market by region, 2007-14 ($m)
Table 3.15: Market for restriction and detection of repeats and unusual patterns by region, 2007-14 ($m)
Table 3.16: Transcriptional elements detection market by region, 2007-14 ($m)
Table 3.17: tRNA detection market by region, 2007-14 ($m)
Table 3.18: Global protein function assignment market by product function, 2007-14 ($m)
Table 3.19: Protein function assignment market by region, 2007-14 ($m)
Table 3.20: Protein-protein interactions tools market by region, 2007-14 ($m)
Table 3.21: Market for pattern, motif, profiles, domains and families search by region, 2007-($m)
Table 3.22: Search, computation and analysis of pathways market by region, 2007-14 ($m)
Table 3.23: Protein annotation market by region, 2007-14 ($m)
Table 3.24: Automatic alerts for related new sequences market by region, 2007-14 ($m)
Table 3.25: Global 3D structure analysis and modeling market by product function, 2007-14 ($m)
Table 3.26: 3D structure analysis and modeling market by region, 2007-14 ($m)
Table 3.27: 3D viewers market by region, 2007-14 ($m)
Table 3.28: 3D homology modeling market by region, 2007-14 ($m)
Table 3.29: 3D analysis market by region, 2007-14 ($m)
Table 3.30: RNA analysis tool market by region, 2007-14 ($m)
Table 3.31: Microarray data analysis market by region, 2007-14 ($m)
Table 3.32: Global phylogenetic analysis market by product function, 2007-14 ($m)
Table 3.33: Phylogenetic analysis market by region, 2007-14 ($m)
Table 3.34: Multiple sequence alignment market by region, 2007-14 ($m)
Table 3.35: Organism classification market by region, 2007-14 ($m)
Table 3.36: Sequence alignment tools market by product function, 2007-14 ($m)
Table 3.37: Sequence alignment tools market by region, 2007-14 ($m)
Table 3.38: Sequence analysis (alignment) tools market by product function, 2007-14 ($m)
Table 3.39: Sequence analysis (alignment) tools market by region, 2007-14 ($m)
Table 3.40: Multiple sequence alignment market by region, 2007-14 ($m)
Table 3.41: Phylogenetic tree building market by region, 2007-14 ($m)
Table 3.42: Consensus sequence and translation by region, 2007-14 ($m)
Table 3.43: Lab end-sequence analysis market by product function, 2007-14 ($m)
Table 3.44: Lab end-sequence analysis by region, 2007-14 ($m)
Table 3.45: Primer design market by region, 2007-14 ($m)
Table 3.46: Cloning market by region, 2007-14 ($m)
Table 3.47: Contig assembly market by region, 2007-14 ($m)
Table 3.48: Sequence manipulation tools market by product function, 2007-14 ($m)
Table 3.49: Sequence manipulation tools market by region, 2007-14 ($m)
Table 3.50: Sequence analysis (including sequence manipulation) market by region, 2007-14 ($m)
Table 3.51: Sequence manipulation market by region, 2007-14 ($m)
Table 3.52: Format conversion market by region, 2007-14 ($m)
Table 3.53: Random sequences market by region, 2007-14 ($m)
Table 3.54: Global structural analysis tools market by product function, 2007-14 ($m)
Table 3.55: Structural analysis tools market by region, 2007-14 ($m)
Table 3.56: Global sequence visualization market by product, 2007-14 ($m)
Table 3.57: Sequence visualization market by region, 2007-14 ($m)
Table 3.58: 3D protein structure market by region, 2007-14 ($m)
Table 3.59: Dot plots and others market by region, 2007-14 ($m)
Table 3.60: Graphical and phylogenetic tree viewer and editor market by region, 2007-14 ($m)
Table 3.61: Primary sequence analysis market by region, 2007-14 ($m)
Table 3.62: Physicochemical property alignment market by region, 2007-14 ($m)
Table 3.63: Alignment tools market by region, 2007-14 ($m)
Table 3.64: Tools to predict secondary structure sequence market by region, 2007-14 ($m)
Table 3.65: Global other tools market by product, 2007-14 ($m)
Table 3.66: Other tools market by region, 2007-14 ($m)
Table 3.67: Visualization tools market by product, 2007-14 ($m)
Table 3.68: Visualization tools market by region, 2007-14 ($m)
Table 3.69: Database viewers market by region, 2007-14 ($m)
Table 3.70: Sequence viewers market by region, 2007-14 ($m)
Table 3.71: Molecular viewers market by region, 2007-14 ($m)
Table 3.72: Physical mapping software market by region, 2007-14 ($m)
Table 4.73: Global content/database market by product, 2007-14 ($m)
Table 4.74: Content/database market by region, 2007-14 ($m)
Table 4.75: Global specialized database market by product, 2007-14 ($m)
Table 4.76: Specialized database market by region, 2007-14 ($m)
Table 4.77: Specialized sequence databases market by region, 2007-14 ($m)
Table 4.78: Global genome databases market by product, 2007-14 ($m)
Table 4.79: Genome databases market by region, 2007-14 ($m)
Table 4.80: Collections market by region, 2007-14 ($m)
Table 4.81: Model organism databases market by region, 2007-14 ($m)
Table 4.82: Global specialized protein databases market by product, 2007-14 ($m)
Table 4.83: Specialized protein databases market by region,
Table 4.84: Proteome databases market by region, 2007-14 ($m)
Table 4.85: Protein classification databases market by region, 2007-14 ($m)
Table 4.86: Specific protein family databases market by region, 2007-14 ($m)
Table 4.87: Specialized structural databases market by region, 2007-14 ($m)
Table 4.88: Microarray databases market by region, 2007-14 ($m)
Table 4.89: Pathway databases market by region, 2007-14 ($m)
Table 4.90: 2D-PAGE databases market by region, 2007-14 ($m)
Table 4.91: Global general database market by product, 2007-14 ($m)
Table 4.92: General database market by region, 2007-14 ($m)
Table 4.93: Primary sequence databases market by region, 2007-14 ($m)
Table 4.94: Protein sequence databases market by region, 2007-14 ($m)
Table 4.95: 3D structure databases market by region, 2007-14 ($m)
Table 4.96: Carbohydrate databases market by region, 2007-14 ($m)
Table 5.97: Global services market by product function, 2007-14 ($m)
Table 5.98: Services market by region, 2007-14 ($m)
Table 5.99: Global data analysis services market by product function, 2007-14 ($m)
Table 5.100: Data analysis services market by region, 2007-14 ($m)
Table 5.101: Genomics data analysis market services by region, 2007-14 ($m)
Table 5.102: Proteomics data analysis services market by region, 2007-14 ($m)
Table 5.103: Microarray data analysis services market by region, 2007-14 ($m)
Table 5.104: Modeling & computational bioinformatics services market by region, 2007-14 ($m)
Table 5.105: Global sequencing services market by product function, 2007-14 ($m)
Table 5.106: Sequencing services market by region, 2007-14 ($m)
Table 5.107: High-throughput sequencing market by region, 2007-14 ($m)
Table 5.108: Multiple sequence alignment market by region, 2007-14 ($m)
Table 5.109: Resequencing services market by region, 2007-14 ($m)
Table 5.110: Primer walking market by region, 2007-14 ($m)
Table 5.111: Expression profile clustering and sequence pattern market by region, 2007-14 ($m)
Table 5.112: Shotgun sequencing (bacterial artificial chromosomes and cosmids) market by region,2007-14 ($m)
Table 5.113: Global database management market by product function, 2007-14 ($m)
Table 5.114: Database management market by region, 2007-14 ($m)
Table 5.115: Conception and realization market by region, 2007-14 ($m)
Table 5.116: User interface development market by region, 2007-14 ($m)
Table 5.117: Maintenance market by region, 2007-14 ($m)
Table 5.118: Backup system market by region, 2007-14 ($m)
Table 5.119: Migration market by region, 2007-14 ($m)
Table 5.120: Other services market by region, 2007-14 ($m)
Table 5.121: Other services market by region, 2007-14 ($m)
Table 5.122: Security system market by region, 2007-14 ($m)
Table 5.123: Data-mining services by region, 2007-14 ($m)
Table 5.124: Infrastructure integration services market by region, 2007-14 ($m)
Table 5.125: Knowledge management market by region, 2007-14 ($m)
Table 6.126: Global applications market by product segment, 2007-14 ($m)
Table 6.127: Global molecular medicine market by product segment, 2007-14 ($m)
Table 6.128: Global preventive medicine market by product segment, 2007-14 ($m)
Table 6.129: Global gene therapy market by product segment, 2007-14 ($m)
Table 6.130: Global drug development market by product function, 2007-14 ($m)
Table 6.131: Global other applications market by product function, 2007-14 ($m)
Table 7.132: Market forecast for bioinformatics by region, 2007-14 ($m)
Table 7.133: North American bioinformatics market, 2007-14 ($m)
Table 7.134: European bioinformatics market, 2007-14 ($m)
Table 7.135: Asian bioinformatics market, 2007-14 ($m)
Table 7.136: RoW bioinformatics market, 2007-14 ($m)
Table 9.137: US bioinformatics patents
Table 9.138: US bioinformatics patents (contd 1)
Table 9.139: US bioinformatics patents (contd 2)
Table 9.140: US bioinformatics patents (contd 3)
Table 9.141: European bioinformatics patents
Table 9.142: European bioinformatics patents (contd 1)
Table 9.143: European bioinformatics patents (contd 2)
Table 9.144: Japanese bioinformatics patents
Table 9.145: Japanese bioinformatics patents (contd 1)
Table 9.146: Japanese bioinformatics patents (contd 2)