SPI Infoamtion

Table of Contents

Executive summary

Market overview
Market dynamics
Global DNA sequencing tools & services market
Company profiles

Chapter 1 Market overview

Summary
Evolution of DNA sequencing
DNA sequencing and drug discovery

Defining the market
Need for more reliable and compatible tools
High throughput and next-generation sequencing - attractive growth factors
DNA sequencing tools dominate the market

Protecting DNA sequencing technology
Applications of DNA sequencing

Drug development Clinical trials
Whole genome testing
Toxicology prediction
Identification of drug resistance
Drug discovery

Chapter 2 Market dynamics

Summary
Introduction
Regional markets

North America
Europe
Asia
RoW

Competitive landscape

Recent agreements and collaborations
Recent launches

Market drivers

Funding from public institutes
NGS technologies
Patient profiling for genetic disorders
Development of personalized medicine
High productivity rates

Market restraints

Shift in sequencing market trends
Introduction of NGS technologies

Chapter 3 Global DNA sequencing tools & services market

Summary
DNA sequencing tools

Microarray

Biochip microarray
Gel array
Array design kit
Low and high density microarrays

Bioinformatics
Electrophoresis

Gel electrophoresis
Capillary electrophoresis

DNA sequencing kits
Consumables, chemicals, reagents and probes

DNA polymerase
Primers

Automated DNA sequencers
Chromatography
DNA amplification (PCR)
Mass spectrometry
Microscopy-based techniques

Electron microscopy
Atomic force microscopy

Microfluidics-enabled workstations
Barcode readers for DNA sample presentation
Computational chemistry and biology modeling
Spotters/arrayers
Centrifuge
Scanners
Thermal cyclers
Charge-coupled devices (CCDs)
Plates, strips and columns

DNA sequencing services

High throughput sequencing
Shotgun sequencing
Re-sequencing
Sample process and primer walking
Single pass analysis
Bacterial identification

Market drivers

Microarray technology is a powerful tool for high throughput screening
Increasing applications of microarrays
Increasing applications of bioinformatics in R&D
Technological breakthroughs generate need for efficient DNA sequencing
Genomics and drug discovery applications of automated sequencers
Diagnostic applications of automated sequencers
Applications in comparative research projects of automated sequencers
Developments in PCR technology
PCR is a reliable tool for multiple applications
Government initiative for funding

Market restraints

Limited scope of microarrays for pathogen enumeration
Time loss due to large number of laboratory specific variations for microarrays
Low cost next-generation technologies hinder growth of microarrays
Incompatibility issues of current bioinformatics tools
High cost of modifying supporting products
High cost and reliability issues of PCR technology

Chapter 4 Company profiles

Summary
454 Life Sciences

Company overview
Products and services
Company strategy
Other events

Affymetrix

Company overview
Product and services
Company strategy

Agilent Technologies

Company overview
Products and services
Company strategy

Beckman Coulter, Inc

Company overview
Products and services
Company strategy

Bio-Rad Laboratories

Company overview
Products and services
Company strategy

Caliper Life Sciences

Company overview
Products and services
Company strategy

CapitalBio Corp.

Company overview
Products and services
Company strategy

CombiMatrix Corp.

Company overview
Products and services
Company strategy

Commonwealth Biotechnologies, Inc

Company overview
Products and services
Company strategy

Complete Genomics, Inc

Company overview
Products and services
Company strategy

DNA Vision

Company overview
Products and services
Company strategy

Enzo Biochem, Inc

Company overview
Products and services
Company strategy

EPICENTRE Biotechnologies

Company overview
Products and services
Company strategy

Eurofins MWG Operon

Company overview
Products and services
Company strategy

GE Healthcare

Company overview
Products and services
Company strategy

Gen-Probe Life Sciences

Company overview
Products and services
Company strategy

GVK Biosciences (GVK BIO)

Company overview
Products and services
Company strategy

Helicos BioSciences Corp.

Company overview
Products and services
Company strategy

Illumina, Inc

Company overview
Products and services
Company strategy

Integrated DNA Technologies

Company overview
Products and services
Company strategy

Kapa Biosystems, Inc

Company overview
Products and services
Company strategy

Life Technologies Corp.

Company overview
Products and services
Company strategy

Microchip Biotechnologies, Inc

Company overview
Products and services
Company strategy

Nanogen, Inc

Company overview
Products and services
Company strategy

Ocimum Biosolutions Ltd.

Company overview
Products and services
Company strategy

Pacific Biosciences

Company overview
Company strategy

PamGene

Company overview
Products and services
Company strategy

Promega Corp.

Company overview
Products and services
Company strategy

QIAGEN

Company overview
Products and services
Company strategy

Sequenom

Company overview
Products and services
Company strategy

Shimadzu Biotech

Company overview
Products and services
Company strategy

Siemens Healthcare Diagnostics

Company overview
Products and services
Company strategy

Sigma-Aldrich

Company overview
Products and services
Company strategy

SoftGenetics, LLC.

Company overview
Products and services
Company strategy

Thermo Fisher Scientific, Inc

Company overview
Products and services
Company strategy

Third Wave Technologies, Inc

Company overview
Products and services
Company strategy

VisiGen Biotechnologies

Company overview
Products and services
Company strategy

ZS Genetics

Company overview
Products and services
Company strategy

Chapter 5 Appendix

Glossary
Patents

List of Figures
Figure 1.1: Developments in DNA sequencing
Figure 1.2: DNA sequencing in drug discovery and development
Figure 1.3: DNA sequencing and drug discovery market
Figure 1.4: Relative importance of features of DNA sequencing tools, 2009 versus 2014
Figure 1.5: DNA sequencing market drivers
Figure 1.6: DNA sequencing tools market dynamics
Figure 1.7: Patent analysis by technology, 2007 versus 2009
Figure 1.8: Patent analysis by geography, 2006 versus 2008
Figure 1.9: Patent applications (%) by competitors, 2004- Oct 09
Figure 2.10: Major segments of the global DNA sequencing market (%), 2008-09
Figure 2.11: Competitive landscape (%), 2008-09 42

List of Tables
Table 1.1: Global DNA sequencing market by tools and services ($m), 2007-14
Table 1.2: Global DNA sequencing applications market by applications ($m), 2007-14
Table 1.3: Global drug development market, by applications ($m), 2007-14
Table 1.4: Global drug discovery market, by applications ($m), 2007-14
Table 2.5: Global DNA sequencing market, by geography ($m), 2007-14
Table 2.6: Agreements and collaborations in the DNA sequencing market, 2008-09
Table 2.7: New product, technology & service launch in the DNA sequencing market, 2008-09
Table 2.8: New product, technology & service launch in the DNA sequencing market, 2008-09 (ctd1)
Table 2.9: New product, technology & service launch in the DNA sequencing market, 2008-09 (ctd2)
Table 2.10: New product, technology & service launch in the DNA sequencing market, 2008-09 (ctd3)
Table 3.11: Global DNA sequencing tools market, by geography ($m), 2007-14
Table 3.12: Global DNA sequencing tools market, by products ($m), 2007-14
Table 3.13: Global microarray market, by products ($m), 2007-14
Table 3.14: Global microarray market, by geography ($m), 2007-14
Table 3.15: Global biochip microarray market, by geography ($m), 2007-14
Table 3.16: Global gel array market, by geography ($m), 2007-14
Table 3.17: Global array design kit market, by geography ($m), 2007-14
Table 3.18: Global high and low density microarray market, by geography ($m), 2007-14
Table 3.19: Global bioinformatics market, by products ($m), 2007-14
Table 3.20: Global bioinformatics market, by geography ($m), 2007-14
Table 3.21: Global electrophoresis market, by products ($m), 2007-14
Table 3.22: Global electrophoresis market, by geography ($m), 2007-14
Table 3.23: Global gel electrophoresis market, by geography ($m), 2007-14
Table 3.24: Global capillary electrophoresis market, by geography ($m), 2007-14
Table 3.25: Global DNA sequencing kits and others market, by geography ($m), 2007-14
Table 3.26: Global consumables, chemicals, reagents and probes market, by products ($m), 2007-14
Table 3.27: Global consumables, chemicals, reagents and probes market, by geography ($m), 2007-14
Table 3.28: Global DNA polymerase market, by geography ($m), 2007-14
Table 3.29: Global primers market, by geography ($m), 2007-14
Table 3.30: Global automated DNA sequencers market, by geography ($m), 2007-14
Table 3.31: Global chromatography market, by geography ($m), 2007-14
Table 3.32: Global DNA amplification (PCR) market, by geography ($m), 2007-14
Table 3.33: Global mass spectrometry market, by geography ($m), 2007-14
Table 3.34: Global microscopy-based techniques market, by products ($m), 2007-14
Table 3.35: Global microscopy-based techniques market, by geography, ($m), 2007-14
Table 3.36: Global electron microscopy market, by geography ($m), 2007-14
Table 3.37: Global AFM market, by geography ($m), 2007-14
Table 3.38: Global microfluidics-enabled workstations market, by geography ($m), 2007-14
Table 3.39: Global barcode readers market for DNA sample presentation, by geography ($m), 2007-
Table 3.40: Global computational chemistry and biology modeling market, by geography ($m), 2007-14
Table 3.41: Global spotters/arrayers market, by geography ($m), 2007-14
Table 3.42: Global centrifuge market, by geography ($m), 2007-14
Table 3.43: Global scanners market, by geography ($m), 2007-14
Table 3.44: Global thermal cycler market, by geography ($m), 2007-14
Table 3.45: Global charge-coupled devices market, by geography ($m), 2007-14
Table 3.46: Global plates, strips and columns market by geography ($m), 2007-14
Table 3.47: Global DNA sequencing services market by products ($m), 2007-14
Table 3.48: Global DNA sequencing services market, by geography ($m), 2007-14
Table 3.49: Global high throughput sequencing market, by geography ($m), 2007-14
Table 3.50: Global shotgun sequencing market, by geography ($m), 2007-14
Table 3.51: Global re-sequencing market, by geography ($m), 2007-14
Table 3.52: Global sample process and primer walking market by geography ($m), 2007-14
Table 3.53: Global single pass analysis market, by geography ($m), 2007-14
Table 3.54: Global bacterial identification market, by geography ($m), 2007-14
Table 5.55: US patents
Table 5.56: US patents (ctd 1)
Table 5.57: US patents (ctd 2)
Table 5.58: US patents (ctd 3)
Table 5.59: US patents (ctd 4)
Table 5.60: US patents (ctd 5)
Table 5.61: US patents (ctd 6)
Table 5.62: US patents (ctd 7)
Table 5.63: US patents (ctd 8)
Table 5.64: European patents
Table 5.65: European patents (ctd 1)
Table 5.66: European patents (ctd 2)
Table 5.67: European patents (ctd 3)
Table 5.68: European patents (ctd 4)
Table 5.69: European patents (ctd 5)
Table 5.70: European patents (ctd 6)
Table 5.71: European patents (ctd 7)
Table 5.72: European patents (ctd 7)
Table 5.73: European patents (ctd 8)
Table 5.74: European patents (ctd 9)
Table 5.75: European patents (ctd 10)
Table 5.76: European patents (ctd 11)
Table 5.77: Japanese patents
Table 5.78: Japanese patents (ctd 2)
Table 5.79: Japanese patents (ctd 3)
Table 5.80: Japanese patents (ctd 4)