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Chapter- 1: INTRODUCTION
STUDY GOALS AND OBJECTIVES
REASONS FOR DOING THE STUDY
SCOPE OF REPORT
METHODOLOGY
RELATED BCC REPORTS
ANALYST CREDENTIALS
BCC ONLINE SERVICES
DISCLAIMER

Chapter-2: SUMMARY
OPHTHALMIC MARKET: MAJOR MARKETS SUMMARY
SUMMARY TABLE TOTAL GLOBAL OPHTHALMIC DIAGNOSTIC, DEVICE, AND SURGICAL MARKET, BY SEGMENT, THROUGH 2014 ($ MILLIONS)
SUMMARY FIGURE TOTAL GLOBAL OPHTHALMIC DIAGNOSTIC, DEVICE, AND SURGICAL MARKET, BY SEGMENT, 2007-2014 ($ MILLIONS)
LEADING MANUFACTURERS

Chapter-3: INDUSTRY OVERVIEW
OVERVIEW OF VISION
STRUCTURE OF THE EYE
PATHOLOGY OF VISION
TERMINOLOGY
TABLE 1 GLOSSARY OF TERMS USED IN OPHTHALMOLOGY
EYE TREATMENT SPECIALISTS
OPHTHALMOLOGIST
OPTOMETRIST
OPTICIAN
U.S. EYE STATISTICS
TABLE 2 ESTIMATED U.S. INCIDENCE AND PREVALENCE OF SELECTED EYE CONDITIONS AND DISEASES
FIGURE 1 ESTIMATED U.S. DISTRIBUTION OF SELECTED EYE CONDITIONS AND DISEASES (%)
GLOBAL EYE STATISTICS
TABLE 3 GLOBAL PREVALENCE OF COMMON OPHTHALMIC CONDITIONS (MILLIONS)
FIGURE 2 ESTIMATED GLOBAL DISTRIBUTION OF SELECTED EYE CONDITIONS AND DISEASES (MILLIONS)
REFRACTIVE ERROR STATISTICS
DESCRIPTION OF OPHTHALMIC CONDITIONS AND DISEASES
DIABETIC RETINOPATHY
AGE-RELATED MACULAR DEGENERATION
OCULAR ALLERGIES
HERPES SIMPLEX VIRUS KERATITIS
CYTOMEGALOVIRUS RETINITIS
CATARACTS
GLAUCOMA
TABLE 4 GLAUCOMA TYPES AND KEY POINTS
UVEITIS
TABLE 5 KNOWN CAUSES OF UVEITIS
TRACHOMA
RETINAL DETACHMENT
DRY EYE SYNDROME
STRABISMUS
TABLE 6 STRABISMUS TYPES AND RELATED CATEGORIES
OCULAR MUSCLE SPASMS

Chapter-4: MARKET TRENDS AND ISSUES
GOVERNMENT REGULATION FOR MEDICAL DEVICES
U.S. DEVICE REGISTRATION PROCESS
EUROPEAN UNION (EU) DEVICE REGISTRATION PROCESS
JAPAN’S DEVICE REGISTRATION PROCESS
THE FDA’S PRECAUTIONS INVOLVING LASIK EYE SURGERY
OPHTHALMIC PHARMACEUTICAL/DEVICE RECALLS AND LABEL UPDATES
TABLE 7 VISION PRODUCT RECALLS, 2004-2010
GOVERNMENT INTERACTION
TABLE 8 GOVERNMENT BILLS/LAWS RELATED TO CONTACT LENSES AND THEIR MANUFACTURERS
FAIRNESS TO CONTACT LENS CONSUMERS ACT
ADVERTISING AND MARKETING
TABLE 9 MARKETING AND ADVERTISING EXPENSES FOR SELECTED OPHTHALMIC MANUFACTURERS/PROVIDERS, 2009 ($ MILLIONS)
REFRACTIVE SURGERY PRICES
HOYA CORPORATION LENS SIMULATION CENTER
GLOBAL POPULATION DEMOGRAPHICS
TABLE 10 GLOBAL POPULATION BY SELECTED COUNTRY, THROUGH 2014 (MILLIONS)
FIGURE 3 GLOBAL POPULATION BY SELECTED COUNTRY, 2007--2014 (MILLIONS)
INDUSTRY ACQUISITIONS AND MERGERS
ADVANCED MEDICAL OPTICS AND ABBOTT MEDICAL OPTICS
OPKO HEALTH
ALCON
OTHERS

Chapter-5: OPHTHALMIC DIAGNOSTICS
OVERVIEW
TYPES OF DIAGNOSTIC TESTS
Visual Acuity Test
Dilated Eye Exam
Manifest Refraction
Pupil Reflex
Tonometry Test
Ophthalmoscopy
Gonioscopy
Slit-lamp Examinations
Fluorescein Staining
Eye Muscle Tests
Corneal Thickness
Pachymetry
Echography
PRODUCT DESCRIPTION
IMAGING DIAGNOSTICS
Optic Nerve Imaging and Related Imaging Technologies
Aberrometer
Echography and Ophthalmic Ultrasound
Corneal Topography
Fluorescein Angiography
Slit-lamp Photography
TABLE 11 SELECT CONDITIONS FOUND THROUGH SLIT-LAMP PHOTOGRAPHY
Specular Microscopy
Glaucoma-scope
Fundus Cameras
NONIMAGING DIAGNOSTICS
Tonometer
Ophthalmoscope
Gonioscope
Slit Lamps
Pachymeter
Perimeter
KEY PRODUCTS
3D OCT System from Topcon
Topcon’s CA-200 Corneal Analyzer
Topcon’s SL-3G Slit Lamp
VISX WaveScan System
Alcon’s LADARWave Wavefront Device
Alcon’s ALLEGRO Family of Diagnostics
ALLEGRO Analyzer
ALLEGRO Oculyzer
ALLEGRO Topolyzer
Bausch & Lomb Zywave Aberrometer
Humphrey Field Analyzer from Carl Zeiss Meditec
Carl Zeiss IOLMaster
Carl Zeiss CRS-Master II Topography Wavefront System
Carl Zeiss Stratus OCT
Carl Zeiss VISUCAM
Carl Zeiss Cirrus HD-OCT
Canon CF-1 and CR-1 Digital Retinal Cameras
Spectralis HRA+OCT by Heidelberg Engineering
Tomey/Eyelogic ARS-8000 Automated Refraction System
Tomey TMS-4A Corneal Topographer
Tomey RT-7000 Auto Ref-Keratometer/Topographer
Tomey OA-1000 Optical Biometer
Tomey TMS-5 Scheimpflug Topographer
Nidek Orion Auto-Retinal Imaging Device
Nidek AFC-210 Fundus Camera
Optos’ P200MA
OPKO Health OCT/SLO
Kowa a-D 5MEGA Nonmydriatic Fundus Camera with VK-2 Digital Imaging Software and the Kowa Nonmyd 7
MARKET SIZE AND GROWTH
TABLE 12 GLOBAL MARKET FOR OPHTHALMIC DIAGNOSTIC EQUIPMENT, BY MARKET SEGMENT, THROUGH 2014 ($ MILLIONS)
FIGURE 4 GLOBAL MARKET FOR OPHTHALMIC DIAGNOSTIC EQUIPMENT, BY MARKET SEGMENT, 2007-2014 ($ MILLIONS)
Markets by Product Type
Imaging/Digital Equipment
TABLE 13 GLOBAL MARKET FOR OPHTHALMIC IMAGING EQUIPMENT BY PRODUCT TYPE, THROUGH 2014 ($ MILLIONS)
FIGURE 5 GLOBAL MARKET FOR OPHTHALMIC IMAGING EQUIPMENT BY PRODUCT TYPE, 2007-2014 ($ MILLIONS)
Nonimaging/Routine Exam Equipment
TABLE 14 GLOBAL MARKET FOR OPHTHALMIC NONIMAGING DIAGNOSTICS/EQUIPMENT BY PRODUCT TYPE, THROUGH 2014 ($ MILLIONS)
FIGURE 6 GLOBAL MARKET FOR OPHTHALMIC NONIMAGING DIAGNOSTICS/EQUIPMENT BY PRODUCT TYPE, 2007-2014 ($ MILLIONS)
Markets by World Region
TABLE 15 GLOBAL MARKET FOR OPHTHALMIC DIAGNOSTIC EQUIPMENT BY GEOGRAPHIC REGION, THROUGH 2014 ($ MILLIONS)
FIGURE 7 GLOBAL MARKET FOR OPHTHALMIC DIAGNOSTIC EQUIPMENT BY GEOGRAPHIC REGION, 2009 AND 2014 ($ MILLIONS)
COMPETITIVE STRUCTURE AND MARKET SHARE
TABLE 16 COMPETITIVE MARKET SHARE FOR OPHTHALMIC DIAGNOSTICS BY MANUFACTURERS’ REVENUES, 2009 ($ MILLIONS/%)
FIGURE 8 COMPETITIVE MARKET SHARE FOR OPHTHALMIC DIAGNOSTICS BY MANUFACTURERS’ REVENUES, 2009 (%)

Chapter-6: VISION CORRECTION AND VISION PRESERVATION DEVICES
OVERVIEW
PRODUCT DESCRIPTION
Contact Lens Products
Soft (Disposable) Lenses
Bausch & Lomb
Ciba Vision
CooperVision
Johnson & Johnson Vision Care and Vistakon
Gas Permeable Lenses
Bausch & Lomb
Cosmetic Lenses
Ciba Vision
CooperVision
Vistakon
Shaping Lenses
Bausch & Lomb
Paragon Vision Sciences
RESEARCH AND DEVELOPMENT
MARKET SIZE AND GROWTH
TABLE 17 TOTAL GLOBAL MARKET FOR CONTACT LENSES, BY MARKET SEGMENT, THROUGH 2014 ($ MILLIONS)
FIGURE 9 TOTAL GLOBAL MARKET FOR CONTACT LENSES, BY MARKET SEGMENT, 2007-2014 ($ MILLIONS)
SOFT CONTACT LENS MARKET BY PRODUCT TYPE
TABLE 18 GLOBAL MARKET FOR SOFT CONTACT LENSES BY PRODUCT TYPE, THROUGH 2014 ($ MILLIONS)
FIGURE 10 GLOBAL MARKET FOR SOFT CONTACT LENSES BY PRODUCT TYPE, 2007-2014 ($ MILLIONS)
MARKETS BY WORLD REGION
TABLE 19 GLOBAL MARKET FOR CONTACT LENSES BY GEOGRAPHIC REGION, THROUGH 2014 ($ MILLIONS)
FIGURE 11 GLOBAL MARKET FOR CONTACT LENSES BY GEOGRAPHIC REGION, 2009 AND 2014 ($ MILLIONS)
COMPETITIVE STRUCTURE AND MARKET SHARE
TABLE 20 COMPETITIVE MARKET SHARE FOR CONTACT LENSES BY MANUFACTURERS’ REVENUES, 2009 ($ MILLIONS/%)
FIGURE 12 COMPETITIVE MARKET SHARE FOR CONTACT LENSES BY MANUFACTURERS’ REVENUES, 2009 ($ MILLIONS)

Chapter-7: SURGICAL EQUIPMENT
OVERVIEW
TYPES OF SURGICAL PROCEDURES
Corneal Procedures
Intracorneal Rings
Cornea Transplants (Penetrating Keratoplasty)
Deep Anterior Lamellar Corneal Transplant (DLEK)
Descemet’s Stripping with Endothelial Keratoplasty (DSEK)
Lens Procedures
Verisyse Lens Implant
Lens Replacements
Refractive Procedures
Mechanical Microkeratome
Blade-free Microkeratome
LASEK, LASIK, AND PRK
Retinal Procedures
Vitreo-retinal Surgery
Surgical Procedures for Cataracts
Phacoemulsification Cataract Surgery
Endocapsular Tension Ring
TABLE 21 ENDOSCAPULAR TENSION RINGS AVAILABLE BY MANUFACTURER
Surgical Procedures for Glaucoma
Glaucoma Implant
Neodymium:YAG Laser Cyclophotocoagulation (YAG CP)
Diode Laser Transscleral Cyclophotocoagulation (Diode CYC)
Selective Laser Trabeculoplasty (SLT)
Argon Laser Trabeculoplasty (ALT)
Laser Peripheral Iridotomy (LPI)
Filtering Microsurgery
Procedures for Age-related Macular Degeneration (AMD)
Focal Laser Treatment and Photodynamic Therapy (PDT)
PRODUCT DESCRIPTION
OPHTHALMIC LASERS
Blade-free Femtosecond Microkeratome
TABLE 22 MICROKERATOME/FEMTOSECOND SYSTEMS BY MANUFACTURER
Excimer Laser
TABLE 23 EXCIMER LASER SYSTEMS BY MANUFACTURER
Nd:YAG Lasers
TABLE 24 SELECT YAG LASER SYSTEMS BY MANUFACTURER
Other Laser Systems
PHACOEMULSIFICATION SYSTEMS
INTRAOCULAR LENSES AND OTHER LENS IMPLANTS
OTHER EQUIPMENT AND DEVICES
Shunts and Drainage Devices
Conductive Keratoplasty (CK)
Radial Keratotomy
Intracorneal Rings (Intacs)
Limbal Relaxing Incisions (LRI)
Viscoelastic Materials/Devices
Retina Stabilizing Adjuncts
KEY PRODUCTS
LASERS AND SURGICAL INSTRUMENTS
Bausch & Lomb’s Hansatome microkeratome
Abbott Medical Optics’ IntraLase FS Laser
VISX Star S4 Laser System
Technolas 217z Laser
Bausch & Lomb’s Orbscan IIz
Alcon’s LADARVision 4000
Carl Zeiss MEL80 Laser System
Nidek EC-5000CX
Allegretto Wave Excimer
LENSES
Alcon
Abbott Medical Optics
STAAR Surgical
RESEARCH AND DEVELOPMENT
MARKET SIZE AND GROWTH
TABLE 25 GLOBAL MARKET FOR OPHTHALMIC SURGICAL EQUIPMENT AND DEVICES, BY MARKET SEGMENT, THROUGH 2014 ($ MILLIONS)
FIGURE 13 TOTAL GLOBAL MARKET FOR OPHTHALMIC SURGICAL EQUIPMENT AND DEVICES, BY MARKET SEGMENT, 2007-2014 ($ MILLION)
Markets by Product Type
Cataract, Vitreoretinal, and Other Eye Conditions
TABLE 26 GLOBAL MARKET FOR OPHTHALMIC SURGICAL EQUIPMENT AND DEVICES FOR CATARACT, VITREORETINAL, AND OTHER EYE CONDITIONS BY PRODUCT TYPE, THROUGH 2014 ($ MILLIONS)
FIGURE 14 GLOBAL MARKET FOR OPHTHALMIC SURGICAL EQUIPMENT AND DEVICES FOR CATARACT, VITREORETINAL, AND OTHER EYE CONDITIONS BY PRODUCT TYPE, 2007-2014 ($ MILLIONS)
Refractive
TABLE 27 GLOBAL MARKET FOR OPHTHALMIC REFRACTIVE SURGERY EQUIPMENT/PRODUCTS BY PRODUCT TYPE, THROUGH 2014 ($ MILLIONS)
FIGURE 15 GLOBAL MARKET FOR OPHTHALMIC REFRACTIVE SURGERY EQUIPMENT/PRODUCTS BY PRODUCT TYPE, 2007-2014 ($ MILLIONS)
Markets by World Region
TABLE 28 GLOBAL MARKET FOR OPHTHALMIC SURGERY EQUIPMENT AND DEVICES BY GEOGRAPHIC REGION, THROUGH 2014 ($ MILLIONS)
FIGURE 16 GLOBAL MARKET FOR OPHTHALMIC SURGERY EQUIPMENT AND DEVICES BY GEOGRAPHIC REGION, 2009 ($ MILLIONS)
COMPETITIVE STRUCTURE AND MARKET SHARE
TABLE 29 COMPETITIVE MARKET SHARE FOR SURGICAL EQUIPMENT AND DEVICE BY MANUFACTURERS’ REVENUES, 2009 ($ MILLIONS)
FIGURE 17 COMPETITIVE MARKET SHARE FOR SURGICAL EQUIPMENT AND DEVICES BY MANUFACTURERS’ REVENUES, 2009 ($ MILLIONS)

Chapter-8: MARKET SUMMARY
TOTAL OPHTHALMIC MARKET
TABLE 30 GLOBAL OPHTHALMIC DIAGNOSTIC, DEVICE, AND SURGICAL MARKET, THROUGH 2014 ($ MILLIONS)
FIGURE 18 GLOBAL OPHTHALMIC MARKET, 2007-2014 ($ MILLIONS)
TOTAL MARKET DISTRIBUTION BY MARKET SEGMENT
TABLE 31 GLOBAL OPHTHALMIC DIAGNOSTIC, DEVICE, AND SURGICAL MARKET, BY MARKET SEGMENT, THROUGH 2014 ($ MILLIONS)
FIGURE 19 GLOBAL OPHTHALMIC DIAGNOSTIC, DEVICE, AND SURGICAL MARKET, BY MARKET SEGMENT, 2007-2014 ($ MILLIONS)
TOTAL MARKET DISTRIBUTION BY GEOGRAPHICAL REGION
TABLE 32 GLOBAL OPHTHALMIC DIAGNOSTIC, DEVICE, AND SURGICAL MARKET, BY GEOGRAPHICAL REGION, THROUGH 2014 ($ MILLIONS)
FIGURE 20 GLOBAL OPHTHALMIC DIAGNOSTIC, DEVICE, AND SURGICAL MARKET, BY GEOGRAPHICAL REGION, 2009 AND 2014 ($ MILLIONS)
INDUSTRY PARTICIPANTS
TABLE 33 INDUSTRY PARTICIPANTS BY PRODUCT TYPE
COMPETITIVE ANALYSIS
TABLE 34 COMPETITIVE ANALYSIS FOR THE OPHTHALMIC MARKET BY TOP PROVIDERS AND REVENUES, 2009 (%/$ MILLIONS)
FIGURE 21 COMPETITIVE ANALYSIS FOR THE OPHTHALMIC MARKET BY TOP PROVIDERS AND REVENUES, 2009 ($ MILLIONS)

Chapter-9: TECHNOLOGY
CURRENT USES OF TECHNOLOGY
ABBOTT MEDICAL OPTIC’S WAVESCAN/CUSTOMVUE TECHNOLOGY
CRYSTALENS BY EYEONICS, INC.
HYBRID LENSES BY SYNERGEYES, INC.
SILICONE HYDROGEL
TABLE 35 EXTENDED WEAR GAS PERMEABLE SOFT LENSES BY BRAND
SENOFILCON A LENS
HIGHLY PERMEABLE LENS TECHNOLOGY
IMPLANTABLE CONTACT LENSES
RETISERT IMPLANT BY BAUSCH & LOMB
ORTHOKERATOLOGY
NIKE MAXSIGHT
TORSIONAL PHACOEMULSIFICATION
ILASIK PROCEDURE
PARADIGM MEDICAL/LACE ELETTRONICA
PATENT EVALUATION
OVERVIEW
PATENT INFORMATION FOR OPHTHALMIC DEVICES
TABLE 36 U.S. OPHTHALMIC DEVICE PATENTS BY FILING DATE
PATENT INFORMATION FOR OPHTHALMIC LASERS
TABLE 37 U.S. OPHTHALMIC LASER PATENTS BY FILING DATE
EVALUATION OF PATENTS BY DATE
Devices
TABLE 38 U.S. OPHTHALMIC DEVICE PATENTS BY YEAR ISSUED, 1976-2010 (TOTAL PATENTS = 303)
FIGURE 22 U.S. OPHTHALMIC DEVICE PATENTS BY YEAR ISSUED, 1976-2010
Lasers
TABLE 39 U.S. OPHTHALMIC LASER PATENTS BY YEAR ISSUED, 1985-2010* (TOTAL PATENTS = 209)
FIGURE 23 U.S. OPHTHALMIC DEVICE PATENTS BY YEAR ISSUED, 1985-2010

Chapter-10: COMPANY PROFILES
PROFILES OVERVIEW
ABBOTT MEDICAL OPTICS
COMPANY OVERVIEW
MARKET PERFORMANCE
TABLE 40 ADVANCED MEDICAL OPTICS REVENUE PERFORMANCE, 2007-2009 ($ MILLIONS)
ALCON, INC.
COMPANY OVERVIEW
MARKET PERFORMANCE
TABLE 41 ALCON REVENUE PERFORMANCE, 2007-2009 ($ MILLIONS)
BAUSCH & LOMB
COMPANY OVERVIEW
MARKET PERFORMANCE
CARL ZEISS AG
COMPANY OVERVIEW
MARKET PERFORMANCE
CIBA VISION
COMPANY OVERVIEW
MARKET PERFORMANCE
COOPERVISION
COMPANY OVERVIEW
MARKET PERFORMANCE
TABLE 42 COOPER COMPANIES REVENUE PERFORMANCE, 2007-2009 ($ MILLIONS)
JOHNSON & JOHNSON VISION CARE
COMPANY OVERVIEW
MARKET PERFORMANCE
TABLE 43 JOHNSON & JOHNSON VISION CARE REVENUE PERFORMANCE, 2007-2009 ($ MILLIONS)
NIDEK
COMPANY OVERVIEW
MARKET PERFORMANCE
TABLE 44 ESTIMATED NIDEK REVENUE PERFORMANCE, 2007-2009 ($ MILLIONS)
STAAR SURGICAL COMPANY
COMPANY OVERVIEW
MARKET PERFORMANCE
TABLE 45 STAAR SURGICAL COMPANY REVENUE PERFORMANCE, 2007-2009 ($ MILLIONS)
TOPCON CORPORATION
COMPANY OVERVIEW
MARKET PERFORMANCE
TABLE 46 TOPCON REVENUE PERFORMANCE, 2007-2009 ($ MILLIONS)

APPENDIX I: OPHTHALMIC PRODUCT MANUFACTURERS
OPHTHALMIC PRODUCT MANUFACTURERS
APPENDIX II: ORGANIZATIONS
ORGANIZATIONS