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TABLE OF CONTENTS

LIST OF FIGURES

LIST OF CHARTS

EXECUTIVE SUMMARY
1.1 OVERVIEW
1.2 RESPONDENT PRACTICE LOCATION
1.3 COMPETING BRANDS
1.4 SYNVISC-ONE® SATISFACTION

SURVEY HIGHLIGHTS
2.1 RESPONDENT CHARACTERISTICS
2.2 RESPONSE SUMMARY
2.2.1 Synvisc-One® Users
2.2.2 Synvisc-One® Non-Users

RESEARCH METHODOLOGY
3.1 RESEARCH METHODOLOGY

SINGLE-CYCLE HYALURONIC ACID VISCOSUPPLEMENTATION SURVEY RESULTS
4.1 QUESTION 1: RESPONDENT EXPERIENCE
4.1.1 Average Years of Practice
4.1.2 Practice Setting
4.2 QUESTION 2: PATIENT VOLUME
4.3 QUESTION 3: BRAND PREFERENCE
4.3.1 Brand Preference by Doctor
4.3.2 Brand Popularity by Total Patient Volume
4.4 QUESTION 4: SYNVISC-ONE® PATIENT PROFILES
4.5 QUESTION 5: SYNVISC-ONE® VERSUS OTHER BRANDS
4.6 QUESTION 6: REASONS FOR USING SYNVISC-ONE®
4.6.1 Summarized Reasons for Choosing Synvisc-One®
4.6.2 Open-Ended Responses for Choosing Synvisc-One®
4.7 QUESTION 7: DOCTOR SATISFACTION
4.7.1 Current Users
4.7.2 Non/Prior Users
4.8 QUESTION 8: PATIENT SATISFACTION
4.9 QUESTION 9: EXPECTED CHANGE IN USAGE
4.9.1 Expected Change in Usage
4.9.2 Expected Change in Usage Versus Satisfaction Rating
4.10 QUESTION 10: REASONS FOR EXPECTED DECREASE IN USAGE

SURVEY QUESTIONS

LIST OF FIGURES
EXECUTIVE SUMMARY
SURVEY HIGHLIGHTS
RESEARCH METHODOLOGY
SINGLE-CYCLE HYALURONIC ACID VISCOSUPPLEMENTATION SURVEY RESULTS
Figure 4-1: Respondent Practice Experience, U.S., 2010
Figure 4-2: Respondent Practice Setting, U.S., 2010
Figure 4-3: Respondent Patient Volume, U.S., 2010
Figure 4-4: Respondent Brand Preference, U.S., 2010
Figure 4-5: Percentage of Respondent Patients Treated per Month by Brand, U.S., 2010
Figure 4-6: New Synvisc-One® Patients, Current Users, U.S., 2010
Figure 4-7: New Synvisc-One® Patients, Prior Users, U.S., 2010
Figure 4-8: Brands Most Frequently Replaced by Synvisc-One®, Current Users, U.S., 2010
Figure 4-9: Brands Most Frequently Replaced by Synvisc-One®, Prior Users, U.S., 2010
Figure 4-10: Reasons for Using Synvisc-One®, Current Users, U.S., 2010
Figure 4-11: Reasons for Having Previously Chosen Synvisc-One®, Prior Users, U.S., 2010
Figure 4-12: Qualitative Reasons Given for Not Using Synvisc-One®, U.S., 2010
Figure 4-13: Doctor Satisfaction with Synvisc-One®, All Current Users, U.S., 2010
Figure 4-14: Doctor Satisfaction with Synvisc-One®, Current Users Who Citied Convenience as a Positive Factor, U.S., 2010
Figure 4-15: Doctor Satisfaction with Synvisc-One®, Non/Prior Users, U.S., 2010
Figure 4-16: Patient Satisfaction with Synvisc-One®, Current Users, U.S., 2010
Figure 4-17: Patient Satisfaction with Synvisc-One®, Prior Users, U.S., 2010
Figure 4-18: Expected Change in Frequency of Synvisc-One® Usage Over the Next Twelve Months, All Current Users, U.S., 2010
Figure 4-19: Expected Change in Frequency of Synvisc-One® Usage Over the Next Twelve Months, Current Users who Cited Convenience as a Positive Factor, U.S., 2010
Figure 4-20: Expected Change in Frequency of Synvisc-One® Usage Over the Next Twelve Months, Prior-Users, U.S., 2010
Figure 4-21: Reasons for Expected Decrease in Synvisc-One® Usage, Current Users, U.S., 2010
SURVEY QUESTIONS

LIST OF CHART S
EXECUTIVE SUMMARY
Chart 1-1: Hyaluronic Acid Usage Among Survey Respondents, U.S., 2010
Chart 1-2: Respondent Location by State, U.S., 2010
Chart 1-3: Brand Preference Among Doctors Who Reported Using Synvisc-One®, U.S., 2010
Chart 1-4: Relative Satisfaction Rating Between Current and Prior Users of Synvisc- One®, U.S., 2010
SURVEY HIGHLIGHTS
RESEARCH METHODOLOGY
SINGLE-CYCLE HYALURONIC ACID VISCOSUPPLEMENTATION SURVEY RESULTS
Chart 4-1: Respondent Practice Experience, Total Respondents, U.S., 2010
Chart 4-2: Respondent Practice Experience, Synvisc-One® Users, U.S., 2010
Chart 4-3: Respondent Practice Experience, Synvisc-One® Non-Users, U.S., 2010
Chart 4-4: Respondent Practice Setting, Total Respondents, U.S., 2010
Chart 4-5: Respondent Practice Setting, Synvisc-One® Users, U.S., 2010
Chart 4-6: Respondent Location by State, U.S., 2010
Chart 4-7: Respondent Patient Volume, Total Respondents, U.S., 2010
Chart 4-8: Respondent Patient Volume, Synvisc-One® Users, U.S., 2010
Chart 4-9: Respondent Patient Volume, Synvisc-One® Non-Users, U.S., 2010
Chart 4-10: Respondent Brand Preference, U.S., 2010
Chart 4-11: Percentage of Respondent Patients Treated per Month by Brand, U.S., 2010
Chart 4-12: New Synvisc-One® Patients, Current Users, U.S., 2010
Chart 4-13: New Synvisc-One® Patients, Prior Users, U.S., 2010
Chart 4-14: Brands Most Frequently Replaced by Synvisc-One®, Current Users, U.S., 2010
Chart 4-15: Reasons for Using Synvisc-One®, Current Users, U.S., 2010
Chart 4-16: Doctor Satisfaction with Synvisc-One®, Current Users, U.S., 2010
Chart 4-17: Doctor Satisfaction with Synvisc-One®, Prior Users, U.S., 2010
Chart 4-18: Years of Practice Versus Doctor Satisfaction with Synvisc-One®, All Users, U.S., 2010
Chart 4-19: Expected Change in Frequency of Synvisc-One® Usage Over the Next Twelve Months, Current Users, U.S., 2010
Chart 4-20: Expected Positive Change in Frequency of Synvisc-One® Usage Over the Next Twelve Months, Current Users, U.S., 2010
Chart 4-21: Expected Change in Frequency of Synvisc-One® Usage Over the Next Twelve Months Compared to Synvisc-One® Satisfaction Rating, U.S., 2010
Chart 4-22: Reasons for Expected Decrease in Synvisc-One® Usage, Current Users, U.S., 2010
SURVEY QUESTIONS