目次

Table of Contents

I. Introduction

II. Major Product Development Opportunities
A. Instrumentation
B. Reagent Kits and Test Systems/panels C. Computers, Software and Automation D. Auxiliary Products

III. Design Criteria for Decentralized Testing Products

IV. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies For Decentralized Testing
Markets

V. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge And Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges

VI. Worldwide Market and Technology Review
A. DNA Sequencing
　1. Introduction
　2. Sequencing Methods
　3. Autoradiography
　4. The Human Genome Project
　5. Sequencing Automation
　6. Image Scanners
　7. Fluorescent Detection
　8. Gene Profiling
　9. Gene Expression
　10. Polymorphism Screening
　11. Protein Interaction Networks
B. DNA and RNA Probe Technologies
　1. Basic Principles
　2. Probe Preparation
　3. The DNA Probe Test
　4. Test Formats
　5. Labeling Techniques
　6. Amplification Methods
C. Detection Technologies
　1. Radioactive Methods a. Overview
　　b. Major Isotopes
　　　　O P-32
　　　　O S-35
　　　　O H-3
　　　　O I-125
　2. Non-Isotopic Methods a. Enzymatic Labels
　　b. Chemical Labeling
　　　　O Indirect Chemical Labeling
　　　　O Direct Chemical Labeling c. Fluorescence
　　d. Chemiluminescence
　　e. Electrical Conductivity
D. Molecular Diagnostic Instrumentation Review
　1. Abbott LCx
　2. Beckman Coulter/Biomek FK
　3. BD Viper System with XTR Technology
　4. BD Innova
　5. Becton Dickinson SDA
　6. bioMerieux NucliSENS easyMAG
　7. bioMerieux NucliSENS easyQ and MiniMAG
　8. Bio-Rad GeneScope
　9. Cepheid GeneXpert
　10. Curetis Unyvero
　11. GenMark Dx eSensor XT-8
　12. Hologic/Gen-Probe Panther
　13. Hologic/Gen-Probe Tigris/DTS
　14. HTG Molecular Edge
　15. Life Technologies QuantStudio Dx
　16. Qiagen QIAsymphony RGQ
　17. Roche Cobas Amplicor
　18. Roche Cobas TaqMan 48
　19. Roche Cobas TaqMan
　20. Roche Cobas TaqMan AmpliPrep
　21. Roche LighCycler 480
　22. Roche Cobas 4800
　23. Roche Cobas s 201
　24. Siemens Versant
　25. Tecan LS Series
E. Biochips: Genosensors, Microarrays, and Labs-on-the-Chip
　　　- Liquid Transportation and Mixing
　　　- Separation
　　　- Reaction
　　　- Detection
F. Pharmacogenomics
G. Major Applications, Microbiology/Infectious Diseases a. Overview
　　b. Major Infectious Diseases
　　　° AIDS: HIV/HIV-1/2/Combo, HIVAg/HIV NAT, Western Blot, HTLV-I/II
　　　° Adenovirus
　　　° Aeromonas
　　　° Anthrax/Bacillus Anthracis
　　　° Arboviruses
　　　° Babesiosis
　　　° Bacillary Epithelioid Angiomatosis (BEA) and Other Bartonella (Rochalimaea)
　　　° Blastocystis Hominis
　　　° Brucella
　　　° Campylobacter
　　　° Candida
　　　° Chagas Disease
　　　° Chancroid
　　　° Chlamydia
　　　° Clostridium Difficile
　　　° Coronaviruses
　　　° Coxsackieviruses
　　　° Creutzfeldt-Jakob’s Disease
　　　° Cryptosporidium Parvum
　　　° Cyclospora Cayetanensis
　　　° Cytomegalovirus
　　　° Ebola Virus
　　　° E. Coli
　　　° EchoVirus
　　　° Encephalitis
　　　° Enteroviruses
　　　° Epstein-Barr Virus
　　　° Giardia Lamblia
　　　° Gonorrhea
　　　° Granuloma Inguinale
　　　° Hantavirus
　　　° Helicobacter Pylori
　　　° Hepatitis: HAV NAT, HBV NAT, HBs Ag, HCV, HCV NAT, Anti-HBc, Anti-HBs, Anti-HAV, Hepatitis Delta, HBc Ag, HBe Ag, ALT/SGPT
　　　° Herpes Simplex Virus
　　　° Human Herpes Virus-6 (HHV-6)
　　　° Influenza Viruses
　　　° Legionella
　　　° Lyme Disease
　　　° Lymphogranuloma Venereum (LGV)
　　　° Malaria
　　　° Measles (Rubeola)
　　　° Meningitis
　　　° Microsporidium
　　　° Mononucleosis
　　　° Mumps
　　　° Mycoplasma
　　　° Papillomaviruses
　　　° Parvovirus B19
　　　° Pneumonia
　　　° Polyomaviruses
　　　° Pseudomonas Aeruginosa
　　　° Rabies
　　　° Respiratory Syncytial Virus (RSV)
　　　° Rhinoviruses
　　　° Rotavirus
　　　° Rubella
　　　° Salmonellosis
　　　° Septicemia
　　　° Shigellosis
　　　° Staphylococcus Aureus
　　　° Streptococci
　　　° Syphilis
　　　° Toxoplasmosis
　　　° Trichomonas Vaginalis
　　　° Tuberculosis
　　　° Vibrio
　　　° West Nile Virus
　　　° Yersina
H. Competing/complementing
　1. Monoclonal Antibodies/Immunoassays
　2. RNA Probes
　3. Two-Dimensional Electrophoresis
　4. Flow Cytometry

VII. U.S. Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts, Major Supplier Sales and Market Shares

VIII. Competitive Assessments
　- Abbott
　- Affymetrix
　- Agilent Technologies
　- Applied Gene Technologies
　- Arca Biopharma
　- Beckman Coulter/Danaher
　- Becton Dickinson
　- Biokit
　- bioMerieux
　- Bio-Rad
　- Biotest
　- Cepheid
　- Decode Genetics
　- Diadexus
　- Eiken Chemical
　- Elitech Group
　- Enzo Biochem
　- Exact Sciences
　- Fujirebio
　- Grifols
　- Hologic
　- Illumina
　- LabCorp
　- Leica Biosystems
　- Li-Cor Biosciences
　- Myriad Genetics
　- Ortho-Clinical Diagnostics
　- PerkinElmer
　- Proteome Sciences
　- Qiagen
　- Roche
　- Scienion
　- Sequenom
　- Shimadzu
　- Siemens Healthineers
　- Sierra Molecular
　- Takara Bio
　- Tecan Group
　- Thermo Fisher

XIII. Appendix: Major Universities and Research Centers
Developing Molecular Diagnostic Technologies

List of Tables
Major Companies Developing or Marketing AIDS Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Bartonella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Campylobacter
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Candida
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Chlamydia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Clostridium
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Coronavirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Cryptosporidium
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing CMV Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Echovirus Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Enterovirus Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Giardia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Gonorrhea
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Hantavirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Helicobacter
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Hepatitis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Herpes
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Influenza
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Legionella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Lyme
Disease Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Measles
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Meningitis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Mononucleosis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Mumps
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Mycoplasma
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Pneumonia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing RSV
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Rotavirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Rubella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Salmonella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Septicemia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Shigella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Streptococci
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Syphilis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Toxoplasmosis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Trichomonas
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Tuberculosis
Molecular Diagnostic and Other Direct
Identification Tests
U.S.A.
Molecular Diagnostics Test Volume And Sales by Major Application 2014-2019
U.S.A.
Laboratories Performing DNA Sequencing by Market Segment 2014
U.S.A.
Molecular Diagnostics Market
Potential Laboratory Universe by Market Segment 2014
U.S.A.
Molecular Diagnostics Test Volume by Major Application 2014-2019
U.S.A.
Major Infectious Disease Test Volume by Assay 2014-2019
U.S.A.
Major Infectious Disease Test Volume by Method 2014
U.S.A.
Molecular Diagnostics Market by Major Application 2014-2019
U.S.A.
Molecular Diagnostics Market
Estimated Sales And Market Shares of Major Suppliers 2014
U.S.A.
Major Infectious Disease Diagnostics Market by Assay 2014-2019
U.S.A.
AIDS Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Adenovirus Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Chlamydia Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
CMV Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Echovirus Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Enterovirus Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
EBV Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Gonorrhea Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Hepatitis Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Hepatitis C Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
HIV/Hepatitis Blood Screening NAT Market
Reagent Sales by Major Supplier 2014
U.S.A.
Herpes Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Influenza Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Meningitis Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Mycoplasma Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Pneumonia Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Rabies Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
RSV Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Salmonella Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
Shigella Testing Market
Estimated Sales by Major Supplier 2014
U.S.A.
West Nile Virus Nat Market
Reagent Sales by Major Supplier 2014