ヒト肝臓モデルは、ヒト肝臓の科学的および技術的表現であり、さまざまな生理学的および病理学的条件におけるその構造、機能、および挙動を研究するために使用されます。これらのモデルは、創薬、毒物学試験、疾患モデリング、再生医療、個別化医療などの用途にとって非常に重要です。従来の肝臓研究は、動物モデルと2D細胞培養に大きく依存していましたが、これらのアプローチは、ヒトの肝臓生理機能を正確に再現するには不十分な場合がよくありました。2024年の世界のヒト肝臓モデルの市場価値は16億4000万ドルで、2030年には38億1000万ドルに達すると予測されます。
世界のヒト肝臓モデル市場は、主に非アルコール性脂肪性肝疾患(NAFLD/MASLD)、アルコール性肝疾患(ALD)、ウイルス性肝炎、肝臓がんなどの肝疾患の有病率の増加によって推進されています。この需要の高まりは、3Dバイオプリンティング、Organ-on-a-chipプラットフォーム、オルガノイドなどの臓器プリンティング技術の進歩によってさらに推進されており、従来の2D細胞培養や動物モデルと比較して、より生理学的に関連性があり、予測可能なヒト肝臓モデルの作成が可能になりました。さらに、倫理的な懸念や、ヒトにおける不正確な医薬品の安全性と有効性の予測につながることが多い固有の種の違いにより、動物実験への依存を減らすことに重点が置かれていることが、ヒト由来の肝臓モデルの採用を大幅に後押ししています。最後に、肝臓がんやその他の肝臓疾患の治療薬に対する需要の高まりと、従来の創薬に関連する高コストと失敗率が相まって、製薬会社やバイオテクノロジー企業は、より効率的な薬物スクリーニング、毒性試験、および個別化医療アプローチのためにこれらの高度なモデルに投資する動機付けとなっています。世界のヒト肝臓モデルの市場価値は、2025年から2030年の予測期間中に15.03%のCAGRで成長すると予想されます。
目次
Table of Contents
1. Executive Summary
2. Introduction
2.1 Human Liver Model: An Overview
2.1.1 Introduction to Human Liver Model
2.1.2 Benefits of Human Liver Model
2.2 Human Liver Model Segmentation: An Overview
2.2.1 Human Liver Model Segmentation
3. Global Market Analysis
3.1 Global Human Liver Model Market: An Analysis
3.1.1 Global Human Liver Model Market: An Overview
3.1.2 Global Human Liver Model Market by Value
3.1.3 Global Human Liver Model Market by Product Type (2D Human Liver Model and 3D Human Liver Model)
3.1.4 Global Human Liver Model Market by Application (ADME Studies, Toxicology Testing, Disease Modeling and Others)
3.1.5 Global Human Liver Model Market by End-use (Pharmaceutical & Biotechnology Companies, Contract Research Organizations and Academic and Research Institutes)
3.1.6 Global Human Liver Model Market by Region (North America, Europe, Asia Pacific and Rest of the World)
3.2 Global Human Liver Model Market: Product Type Analysis
3.2.1 Global Human Liver Model Market by Product Type: An Overview
3.2.2 Global 2D Human Liver Model Market by Value
3.2.3 Global 2D Human Liver Model Market by Product Type (Cell Lines and Primary Human Hepatocytes)
3.2.4 Global Cell Lines 2D Human Liver Model Market by Value
3.2.5 Global Primary Human Hepatocytes 2D Human Liver Model Market by Value
3.2.6 Global 3D Human Liver Model Market by Value
3.2.7 Global 3D Human Liver Model Market by Product Type (Liver-on-a-chip, Organoids, Spheroids and 3D bio printed tissues)
3.2.8 Global Liver-on-a-chip 3D Human Liver Model Market by Value
3.2.9 Global Organoids 3D Human Liver Model Market by Value
3.2.10 Global Spheroids 3D Human Liver Model Market by Value
3.2.11 Global 3D Bio printed Tissues Human Liver Model Market by Value
3.3 Global Human Liver Model Market: Application Analysis
3.3.1 Global Human Liver Model Market by Application: An Overview
3.3.2 Global ADME Studies Human Liver Model Market by Value
3.3.3 Global Toxicology Testing Human Liver Model Market by Value
3.3.4 Global Disease Modeling Human Liver Model Market by Value
3.3.5 Global Others Human Liver Model Market by Value
3.4 Global Human Liver Model Market: End-use Analysis
3.4.1 Global Human Liver Model Market by End-use: An Overview
3.4.2 Global Pharmaceutical & Biotechnology Companies Human Liver Model Market by Value
3.4.3 Global Contract Research Organizations Human Liver Model Market by Value
3.4.4 Global Academic and Research Institutes Human Liver Model Market by Value
4. Regional Market Analysis
4.1 North America Human Liver Model Market: An Analysis
4.1.1 North America Human Liver Model Market: An Overview
4.1.2 North America Human Liver Model Market by Value
4.1.3 North America Human Liver Model Market by Region (The US, Canada and Mexico)
4.1.4 The US Human Liver Model Market by Value
4.1.5 Canada Human Liver Model Market by Value
4.1.6 Mexico Human Liver Model Market by Value
4.2 Europe Human Liver Model Market: An Analysis
4.2.1 Europe Human Liver Model Market: An Overview
4.2.2 Europe Human Liver Model Market by Value
4.2.3 Europe Human Liver Model Market by Region (Germany, UK, France, Italy, Spain and Rest of Europe)
4.2.4 Germany Human Liver Model Market by Value
4.2.5 United Kingdom Human Liver Model Market by Value
4.2.6 France Human Liver Model Market by Value
4.2.7 Italy Human Liver Model Market by Value
4.2.8 Spain Human Liver Model Market by Value
4.2.9 Rest of Europe Human Liver Model Market by Value
4.3 Asia Pacific Human Liver Model Market: An Analysis
4.3.1 Asia Pacific Human Liver Model Market: An Overview
4.3.2 Asia Pacific Human Liver Model Market by Value
4.3.3 Asia Pacific Human Liver Model Market by Region (China, Japan, India, South Korea and Rest of Asia Pacific)
4.3.4 China Human Liver Model Market by Value
4.3.5 Japan Human Liver Model Market by Value
4.3.6 India Human Liver Model Market by Value
4.3.7 South Korea Human Liver Model Market by Value
4.3.8 Rest of Asia Pacific Human Liver Model Market by Value
4.4 Rest of the World Human Liver Model Market: An Analysis
4.4.1 Rest of the World Human Liver Model Market: An Overview
4.4.2 Rest of the World Human Liver Model Market by Value
5. Market Dynamics
5.1 Growth Drivers
5.1.1 Increasing Prevalence of Liver Diseases
5.1.2 Growing Demand for Alternatives to Animal Testing
5.1.3 Increasing Focus on Personalized Medicine
5.1.4 Growing Investment in Liver Research
5.1.5 The Growing Need for Early Drug Toxicity Diagnosis
5.2 Challenges
5.2.1 High Cost of Liver Models
5.2.2 Dearth of Skilled Professionals
5.3 Market Trends
5.3.1 Integration of AI and Machine Learning
5.3.2 Advancements in Organ Printing and Tissue Engineering Technologies
5.3.3 Shift from 2D to Advanced 3D and Ex Vivo Models
5.3.4 Rise of Hybrid and In Silico Models
6. Competitive Landscape
6.1 Global Human Liver Model Market Players: Competitive Landscape
6.1.1 Global Human Liver Model Market Players: An Overview
6.2 Global Human Liver Model Market Players: Recent Developments
7. Company Profiles
7.1 Corning Incorporated
7.1.1 Business Overview
7.1.2 Operating Segments
7.1.3 Business Strategies
7.2 Organovo Holdings Inc.
7.2.1 Business Overview
7.2.2 Business Strategies
7.3 InSphero AG
7.3.1 Business Overview
7.3.2 Business Strategies
7.4 BioIVT LLC
7.4.1 Business Overview
7.4.2 Business Strategies
7.5 Emulate Inc.
7.5.1 Business Overview
7.5.2 Business Strategies
7.6 MatTek (The BICO Group)
7.6.1 Business Overview
7.6.2 Business Strategies
7.7 MIMETAS
7.7.1 Business Overview
7.7.2 Business Strategies
7.8 CN Bio Innovations Ltd.
7.8.1 Business Overview
7.8.2 Business Strategies
7.9 Cyfuse Biomedical K.K.
7.9.1 Business Overview
7.9.2 Business Strategies
7.10 PhoenixBio Co., Ltd.
7.10.1 Business Overview
7.10.2 Business Strategies
7.11 STEMCELL Technologies
7.11.1 Business Overview
7.11.2 Business Strategies
7.12 Pandorum Technologies Pvt. Ltd.
7.12.1 Business Overview
7.13 Kirkstall Ltd.
7.13.1 Business Overview
List of Figures
Figure 1: Benefits of Human Liver Model
Figure 2: Human Liver Model Segmentation
Figure 3: Global Human Liver Model Market by Value; 2020-2024 (US$ Billion)
Figure 4: Global Human Liver Model Market by Value; 2025-2030 (US$ Billion)
Figure 5: Global Human Liver Model Market by Product Type; 2024 (Percentage, %)
Figure 6: Global Human Liver Model Market by Application; 2024 (Percentage, %)
Figure 7: Global Human Liver Model Market by End-use; 2024 (Percentage, %)
Figure 8: Global Human Liver Model Market by Region; 2024 (Percentage, %)
Figure 9: Global 2D Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 10: Global 2D Human Liver Model Market by Value; 2025-2030 (US$ Billion)
Figure 11: Global 2D Human Liver Model Market by Product Type; 2024 (Percentage, %)
Figure 12: Global Cell Lines 2D Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 13: Global Cell Lines 2D Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 14: Global Primary Human Hepatocytes 2D Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 15: Global Primary Human Hepatocytes 2D Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 16: Global 3D Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 17: Global 3D Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 18: Global Human Liver Model Market by Product Type; 2024 (Percentage, %)
Figure 19: Global Liver-on-a-chip 3D Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 20: Global Liver-on-a-chip 3D Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 21: Global Organoids 3D Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 22: Global Organoids 3D Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 23: Global Spheroids 3D Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 24: Global Spheroids 3D Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 25: Global 3D Bio printed Tissues Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 26: Global 3D Bio printed Tissues Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 27: Global ADME Studies Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 28: Global ADME Studies Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 29: Global Toxicology Testing Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 30: Global Toxicology Testing Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 31: Global Disease Modeling Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 32: Global Disease Modeling Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 33: Global Others Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 34: Global Others Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 35: Global Pharmaceutical & Biotechnology Companies Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 36: Global Pharmaceutical & Biotechnology Companies Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 37: Global Contract Research Organizations Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 38: Global Contract Research Organizations Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 39: Global Academic and Research Institutes Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 40: Global Academic and Research Institutes Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 41: North America Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 42: North America Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 43: North America Human Liver Model Market by Region; 2024 (Percentage, %)
Figure 44: The US Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 45: The US Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 46: Canada Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 47: Canada Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 48: Mexico Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 49: Mexico Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 50: Europe Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 51: Europe Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 52: Europe Human Liver Model Market by Region; 2024 (Percentage, %)
Figure 53: Germany Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 54: Germany Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 55: United Kingdom Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 56: United Kingdom Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 57: France Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 58: France Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 59: Italy Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 60: Italy Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 61: Spain Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 62: Spain Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 63: Rest of Europe Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 64: Rest of Europe Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 65: Asia Pacific Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 66: Asia Pacific Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 67: Asia Pacific Human Liver Model Market by Region; 2024 (Percentage, %)
Figure 68: China Human Liver Model Market by Value, 2020-2024 (US$ Million)
Figure 69: China Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 70: Japan Human Liver Model Market by Value, 2020-2024 (US$ Million)
Figure 71: Japan Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 72: India Human Liver Model Market by Value, 2020-2024 (US$ Million)
Figure 73: India Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 74: South Korea Human Liver Model Market by Value, 2020-2024 (US$ Million)
Figure 75: South Korea Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 76: Rest of Asia Pacific Human Liver Model Market by Value, 2020-2024 (US$ Million)
Figure 77: Rest of Asia Pacific Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 78: Rest of the World Human Liver Model Market by Value; 2020-2024 (US$ Million)
Figure 79: Rest of the World Human Liver Model Market by Value; 2025-2030 (US$ Million)
Figure 80: Global Artificial Intelligence (AI) in Healthcare Market; 2021-2030 (US$ Billion)
Figure 81: Corning Incorporated Net Sales by Segments; 2024 (Percentage, %)
